SCHEMBL8445574

SCHEMBL8445574

CC1(C)C(=O)N(CC#CI)C(=O)N1CC#CI

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8445120 0.84 RAB9A (0.36) RAB9A
SCHEMBL8441783 0.82 PTGS1 (0.38) RAB9A
SCHEMBL8442425 0.81 ELANE (0.45)
SCHEMBL11532007 0.74 AR (0.44) RAB9A
SCHEMBL8997578 0.74 RAB9A (0.37) RAB9A
SCHEMBL8440701 0.73 POLB (0.57)
SCHEMBL7569486 0.72 AR (0.44)
SCHEMBL11696234 0.65 F2 (0.46) RAB9A
SCHEMBL1536279 0.64 LMNA (0.42) RAB9A
SCHEMBL17160622 0.62 RAB9A (0.36) RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0572191-B1 N-iodopropargyl hydantoin compounds, compositions, preparation, and use as antimicrobial agents ROHM & HAAS (US) 1996-09-04 EP claimed
US-5346913-A Agricultural fungicides ROHM AND HAAS COMPANY (US) 1994-09-13 US claimed
EP-0572191-A1 N-iodopropargyl hydantoin compounds, compositions, preparation, and use as antimicrobial agents ROHM AND HAAS COMPANY (US) 1993-12-01 EP claimed
US-6008244-A APPLYING ONTO OR INTO THE MARINE STRUCTURE TO INHIBIT GROWTH SUCH AS SOFT CORALS, TUNICATES, HYDROIDS, SPONGES, ANEMONES, BARNACLES, TUBEWORMS AND MOLLUSCS ROHM AND HAAS COMPANY (US) 1999-12-28 US disclosed
CN-1180477-A Halopropargyl compounds as marine antifouling agents ROHM & HAAS (US) 1998-05-06 CN disclosed
EP-0835604-A1 Halopropargyl compounds as marine antifouling agents ROHM AND HAAS COMPANY (US) 1998-04-15 EP disclosed
EP-0572191-B1 N-iodopropargyl hydantoin compounds, compositions, preparation, and use as antimicrobial agents ROHM & HAAS (US) 1996-09-04 EP disclosed
US-5346913-A Agricultural fungicides ROHM AND HAAS COMPANY (US) 1994-09-13 US disclosed
EP-0572191-A1 N-iodopropargyl hydantoin compounds, compositions, preparation, and use as antimicrobial agents ROHM AND HAAS COMPANY (US) 1993-12-01 EP disclosed