Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443179 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KMT2APOLBCA12CA1 | |
| SCHEMBL7868642 | 0.80 | CA12 (0.48) | ALDH1A1KMT2APOLBCA12CA1 | |
| SCHEMBL8443490 | 0.79 | CA12 (0.47) | ALDH1A1KMT2APOLBCA12CA1 | |
| SCHEMBL8443583 | 0.79 | CA12 (0.47) | ALDH1A1KMT2APOLBCA12CA1 | |
| SCHEMBL16320413 | 0.78 | KMT2A (0.53) | ALDH1A1KMT2APOLBCA12CA1 | |
| SCHEMBL7875320 | 0.78 | DRD4 (0.60) | ALDH1A1KMT2APOLBCA12CA1 | |
| SCHEMBL10853038 | 0.78 | TMEM97 (0.51) | ALDH1A1CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL8446831 | 0.78 | CA12 (0.46) | ALDH1A1KMT2APOLBCA12CA1 | |
| SCHEMBL11248409 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KMT2APOLBCA12CA1 | |
| SCHEMBL27220883 | 0.76 | ALDH1A1 (0.67) | ALDH1A1KMT2APOLBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618907-B1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | BRITISH TECH GROUP INT (GB) | 1999-04-28 | — | — | EP | claimed |