Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243418 | 0.95 | ALDH1A1 (0.53) | ALDH1A1KMT2APOLBCYP1A2CYP3A4 | |
| SCHEMBL11247290 | 0.92 | NPSR1 (0.55) | ALDH1A1KMT2APOLBCYP1A2CYP3A4 | |
| SCHEMBL7875320 | 0.88 | DRD4 (0.60) | ALDH1A1KMT2APOLBDRD2DRD4 | |
| SCHEMBL7292248 | 0.82 | MEN1 (0.54) | ALDH1A1KMT2APOLBCYP1A2CYP3A4 | |
| SCHEMBL11151507 | 0.79 | KMT2A (0.44) | ALDH1A1KMT2APOLBKCNH2KDM4E | |
| SCHEMBL7293790 | 0.77 | GAA (0.58) | ALDH1A1KMT2APOLBCYP1A2CYP3A4 | |
| SCHEMBL23657179 | 0.77 | ALDH1A1 (0.65) | ALDH1A1KMT2APOLBCYP19A1KDM4E | |
| SCHEMBL11240131 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KMT2APOLBL3MBTL1KDM4E | |
| SCHEMBL11251413 | 0.77 | KDM4E (0.49) | ALDH1A1KMT2APOLBKCNH2KDM4E | |
| SCHEMBL8445718 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KMT2APOLBKCNH2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049060-A1 | Imidazoles | BEECHAM GROUP PLC (GB) | 1982-04-07 | — | — | EP | disclosed |