Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8421637 | 0.98 | TSHR (0.47) | TSHRRXFP1KMT2AMEN1LMNA | |
| Hydrochloric Acid SCHEMBL3418048 | 0.85 | TSHR (0.46) | TSHRRXFP1KMT2AMEN1LMNA | |
| SCHEMBL515612 | 0.82 | RXFP1 (0.60) | TSHRRXFP1KMT2AMEN1CYP2C19 | |
| SCHEMBL684242 | 0.78 | CYP2D6 (0.52) | TSHRKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL1054300 | 0.78 | CYP2C19 (0.50) | TSHRRXFP1KMT2AMEN1CYP2C19 | |
| SCHEMBL8664912 | 0.78 | TSHR (0.54) | TSHRRXFP1KMT2AMEN1CYP2C19 | |
| SCHEMBL3455609 | 0.78 | ADORA2B (0.52) | TSHRRXFP1KMT2AMEN1CYP2C19 | |
| Hydrochloric Acid SCHEMBL11379641 | 0.77 | CYP2D6 (0.51) | TSHRKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL684262 | 0.76 | TSHR (0.54) | TSHRKMT2AMEN1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11384933 | 0.75 | SMN1; SMN2 (0.55) | TSHRKMT2AMEN1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642781-B1 | Stable acid oil-in-water emulsions | OREAL (FR) | 1999-01-20 | — | — | EP | disclosed |
| EP-0642781-A1 | Stable acid oil-in-water emulsions and compositions containing them | L'OREAL (FR) | 1995-03-15 | — | — | EP | disclosed |