Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 9/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11379641 | 0.99 | CYP2D6 (0.51) | CYP2D6TSHRLMNASMN1; SMN2HTT | |
| SCHEMBL684262 | 0.92 | TSHR (0.54) | CYP2D6TSHRLMNASMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL11384933 | 0.91 | SMN1; SMN2 (0.55) | CYP2D6TSHRLMNASMN1; SMN2HTT | |
| SCHEMBL683535 | 0.91 | TSHR (0.56) | CYP2D6TSHRLMNASMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL11380152 | 0.89 | TSHR (0.55) | CYP2D6TSHRLMNASMN1; SMN2HTT | |
| SCHEMBL684229 | 0.87 | TSHR (0.52) | TSHRLMNASMN1; SMN2HTTJAK2 | |
| Hydrochloric Acid SCHEMBL11380619 | 0.86 | TSHR (0.51) | TSHRLMNASMN1; SMN2HTTJAK2 | |
| SCHEMBL684244 | 0.82 | CYP2D6 (0.55) | CYP2D6TSHRSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL683958 | 0.82 | TSHR (0.54) | TSHRLMNASMN1; SMN2HTTJAK2 | |
| Hydrochloric Acid SCHEMBL11382033 | 0.81 | TSHR (0.53) | TSHRLMNASMN1; SMN2HTTJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4299832-A | Substituted theophylline compounds | FISONS LIMITED (GB) | 1981-11-10 | — | — | US | claimed |
| EP-0011399-A1 | N-substituted theophyllines, processes for their preparation and pharmaceutical compositions containing them | FISONS plc (GB) | 1980-05-28 | — | — | EP | claimed |
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS INC. (US) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | NGF, DCX, BDNF | CYP2D6 4428/4885TSHR 1873/4885LMNA 2155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.