SCHEMBL8445954

SCHEMBL8445954

Oc1ccc(Cl)cc1C(O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.52
TSHR P16473 3/20 0.52
MEN1 O00255 9/20 0.52
KMT2A Q03164 9/20 0.52
MAPT P10636 4/20 0.52
HTT P42858 3/20 0.52
MAPK1 P28482 3/20 0.52
NPSR1 Q6W5P4 1/20 0.52
HPGD P15428 8/20 0.48
ALDH1A1 P00352 6/20 0.48
ALOX15 P16050 5/20 0.48
ALOX12 P18054 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
TDP1 Q9NUW8 4/20 0.47
CYP3A4 P08684 4/20 0.46
HIF1A Q16665 4/20 0.46
HSP90AA1 P07900 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
LMNA P02545 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19954062 0.84 MEN1 (0.50) HSD17B10TSHRMEN1KMT2AMAPT
SCHEMBL2982934 0.82 MEN1 (0.58) HSD17B10TSHRMEN1KMT2AMAPT
SCHEMBL815863 0.79 MEN1 (0.59) HSD17B10TSHRMEN1KMT2AMAPT
SCHEMBL51491 0.79 MEN1 (0.59) HSD17B10TSHRMEN1KMT2AMAPT
SCHEMBL11736296 0.79 MEN1 (0.50) HSD17B10TSHRMEN1KMT2AMAPT
SCHEMBL9854302 0.78 TSHR (0.48) HSD17B10TSHRMEN1KMT2AMAPT
SCHEMBL3745809 0.77 CA1 (0.50) HSD17B10TSHRMEN1KMT2AMAPT
SCHEMBL3745804 0.77 CA1 (0.50) HSD17B10TSHRMEN1KMT2AMAPT
SCHEMBL7077164 0.77 MEN1 (0.45) HSD17B10TSHRMEN1KMT2AMAPT
SCHEMBL27528336 0.77 MEN1 (0.45) HSD17B10TSHRMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101219940-A Parachlorophenol hydroxyl radical resorcinol formaldehyde, production and application in sewage water detection of the same UNIV NORTHWEST NORMAL (CN) 2008-07-16 CN claimed
US-4070318-A VINYL PYRIDINE COPOLYMER RUBBER, CONDENSATION THE GENERAL TIRE & RUBBER COMPANY (US) 1978-01-24 US claimed
JP-2216281-A None JP disclosed
JP-11081150-A None JP disclosed
JP-6158548-A None JP disclosed
JP-10298873-A None JP disclosed
EP-2435407-B1 ARYL SUBSTITUTED CARBOXAMIDE DERIVATIVES AS CALCIUM OR SODIUM CHANNEL BLOCKERS RAQUALIA PHARMA INC (JP) 2019-12-25 EP disclosed
CN-101417961-B Anion receptor based on nitro phenylhydrazone and phenolic hydroxyl and preparation of anion test paper and use thereof UNIV NORTHWEST NORMAL 2012-07-25 CN disclosed
CN-101417989-B Anion receptor based on nitrofuran formyl hydrazone and phenolic hydroxyl and preparation and use of organagel thereof UNIV NORTHWEST NORMAL 2011-05-11 CN disclosed
CN-101417961-A Anion receptor based on nitro phenylhydrazone and phenolic hydroxyl and preparation of anion test paper and use thereof UNIV NORTHWEST NORMAL (CN) 2009-04-29 CN disclosed
CN-101417989-A Anion receptor based on nitrofuran formyl hydrazone and phenolic hydroxyl and preparation and use of organagel thereof UNIV NORTHWEST NORMAL (CN) 2009-04-29 CN disclosed
CN-101219940-A Parachlorophenol hydroxyl radical resorcinol formaldehyde, production and application in sewage water detection of the same UNIV NORTHWEST NORMAL (CN) 2008-07-16 CN disclosed
CN-1277793-C Process for synthesizing 2-hydroxy-3-bromomethyl-5-substituted benzaldehyde DALIAN CHEMICAL PHYSICS INST (CN) 2006-10-04 CN disclosed
CN-1634836-A Process for synthesizing 2-hydroxy-3-bromomethyl-5-substituted benzaldehyde DALIAN CHEMICAL PHYSICS INST (CN) 2005-07-06 CN disclosed
JP-H1181150-A TREATMENT OF POLYESTER YARN FOR REINFORCING RUBBER UNITIKA LTD 1999-03-26 JP disclosed
JP-H10298873-A TREATMENT OF POLYESTER FIBER FOR REINFORCING RUBBER UNITIKA LTD 1998-11-10 JP disclosed
JP-H06158548-A TREATMENT OF POLYESTER FIBER FOR RUBBER REINFORCEMENT UNITIKA LTD 1994-06-07 JP disclosed
JP-H02216281-A METHOD FOR TREATING POLYESTER FIBER FOR REINFORCING RUBBER UNITIKA LTD 1990-08-29 JP disclosed
US-4070318-A VINYL PYRIDINE COPOLYMER RUBBER, CONDENSATION THE GENERAL TIRE & RUBBER COMPANY (US) 1978-01-24 US disclosed