SCHEMBL51491

SCHEMBL51491

CC(c1cc(Cl)ccc1O)c1cc(Cl)ccc1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.59
KMT2A Q03164 8/20 0.59
MAPT P10636 4/20 0.59
HTT P42858 4/20 0.59
MAPK1 P28482 3/20 0.59
NPSR1 Q6W5P4 1/20 0.59
HPGD P15428 7/20 0.54
ALDH1A1 P00352 6/20 0.54
TDP1 Q9NUW8 4/20 0.54
HSD17B10 Q99714 4/20 0.50
TSHR P16473 3/20 0.50
GAA P10253 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ALOX15 P16050 4/20 0.46
ALOX12 P18054 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
GABRA1 P14867 1/20 0.46
GABRB1 P18505 1/20 0.46
TP53 P04637 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15459931 0.92 GABRA1 (0.55) MEN1KMT2AMAPTHTTMAPK1
SCHEMBL15459927 0.92 GABRA1 (0.55) MEN1KMT2AMAPTHTTMAPK1
SCHEMBL11306853 0.89 MEN1 (0.54) MEN1KMT2AMAPTHTTMAPK1
SCHEMBL815863 0.86 MEN1 (0.59) MEN1KMT2AMAPTHTTMAPK1
SCHEMBL574405 0.85 KMT2A (0.59) MEN1KMT2AMAPTHTTMAPK1
SCHEMBL2982934 0.84 MEN1 (0.58) MEN1KMT2AMAPTHTTMAPK1
SCHEMBL15459928 0.83 HIF1A (0.60) MEN1KMT2AMAPTHTTMAPK1
SCHEMBL28310106 0.83 LMNA (0.59) MEN1KMT2AMAPTHTTMAPK1
SCHEMBL26668395 0.83 LMNA (0.59) MEN1KMT2AMAPTHTTMAPK1
SCHEMBL28217357 0.83 LMNA (0.59) MEN1KMT2AMAPTHTTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2714763-B1 EPOXY RESINS WITH HIGH THERMAL STABILITY AND TOUGHNESS HUNTSMAN ADVANCED MAT AMERICAS LLC (US) 2017-03-01 EP disclosed
EP-2181853-B1 Thermosensitive recording medium JUJO PAPER CO LTD (JP) 2015-09-23 EP disclosed
US-9122182-B2 Charge control agent and toner for electrostatic image development containing same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-09-01 US disclosed
US-9122182-B2 Charge control agent and toner for electrostatic image development containing same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-09-01 US disclosed
US-9051415-B2 Epoxy resins with high thermal stability and toughness HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2015-06-09 US disclosed
US-9051415-B2 Epoxy resins with high thermal stability and toughness HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2015-06-09 US disclosed
US-9051498-B2 Epoxy resins with high thermal stability and toughness HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2015-06-09 US disclosed
US-9051498-B2 Epoxy resins with high thermal stability and toughness HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2015-06-09 US disclosed
US-20140296447-A1 Epoxy Resins With High Thermal Stability and Toughness Huntsman Advanced Materials Americans LLC (US) 2014-10-02 US disclosed
US-20140296447-A1 Epoxy Resins With High Thermal Stability and Toughness Huntsman Advanced Materials Americans LLC (US) 2014-10-02 US disclosed
US-20100285269-A1 BASALT PARTICLE-CONTAINING COMPOSITIONS AND ARTICLES FOR PROTECTIVE COATINGS AND BALLISTIC SHIELD MATS/TILES/PROTECTIVE BUILDING COMPONENTS U.S. WIND FARMING, INC. (US) 2010-11-11 US disclosed
EP-2181853-A1 THERMAL RECORDING MATERIAL Nippon Paper Industries Co., Ltd. (JP) 2010-05-05 EP disclosed
US-20100099557-A1 Thermosensitive Recording Medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2010-04-22 US disclosed
US-20100012004-A1 Basalt particle-containing compositions and articles for protective coatings and ballistic shield mats/tiles/protective building components U.S. WIND FARMING INC. (US) 2010-01-21 US disclosed
US-20090067924-A1 HYDROCARBON-ADSORBING POROUS PAVEMENT STRUCTURE KAUL CORPORATION (US) 2009-03-12 US disclosed
US-20090067924-A1 HYDROCARBON-ADSORBING POROUS PAVEMENT STRUCTURE KAUL CORPORATION (US) 2009-03-12 US disclosed
US-20070224401-A1 Basalt particle-containing articles for ballistic shield mats/tiles/protective building components U.S. WIND FARMING INC. (US) 2007-09-27 US disclosed
US-20070224401-A1 Basalt particle-containing articles for ballistic shield mats/tiles/protective building components U.S. WIND FARMING INC. (US) 2007-09-27 US disclosed
US-20070154643-A1 Extrusion coating compositions and method VALSPAR SOURCING, INC. (US) 2007-07-05 US disclosed
US-20070154643-A1 Extrusion coating compositions and method VALSPAR SOURCING, INC. (US) 2007-07-05 US disclosed