Sugi Predict

Sugi Predict / Compounds / SCHEMBL815863

SCHEMBL815863

SCHEMBL815863

CC(C)c1cc(Cl)ccc1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 8/20 0.59
▸ KMT2A Q03164 8/20 0.59
▸ MAPT P10636 4/20 0.59
▸ MAPK1 P28482 3/20 0.59
▸ HTT P42858 3/20 0.59
▸ NPSR1 Q6W5P4 1/20 0.59
▸ GABRA1 P14867 2/20 0.58
▸ GABRB1 P18505 1/20 0.58
▸ HPGD P15428 7/20 0.54
▸ ALDH1A1 P00352 6/20 0.54
▸ TDP1 Q9NUW8 4/20 0.54
▸ LMNA P02545 5/20 0.50
▸ HSD17B10 Q99714 4/20 0.50
▸ TSHR P16473 3/20 0.50
▸ GAA P10253 2/20 0.50
▸ L3MBTL1 Q9Y468 2/20 0.50
▸ KDM4E B2RXH2 1/20 0.50
▸ GABRB2 P47870 1/20 0.48
▸ ALOX15 P16050 4/20 0.46
▸ ALOX12 P18054 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51491 0.86 MEN1 (0.59) MEN1KMT2AMAPTMAPK1HTT
SCHEMBL2982934 0.84 MEN1 (0.58) MEN1KMT2AMAPTMAPK1HTT
SCHEMBL28217357 0.83 LMNA (0.59) MEN1KMT2AMAPTMAPK1HTT
SCHEMBL26668395 0.83 LMNA (0.59) MEN1KMT2AMAPTMAPK1HTT
SCHEMBL28310106 0.83 LMNA (0.59) MEN1KMT2AMAPTMAPK1HTT
SCHEMBL10053115 0.82 LMNA (0.59) MEN1KMT2AMAPTMAPK1HTT
SCHEMBL8469992 0.81 RORC (0.58) MEN1KMT2AMAPTMAPK1HTT
SCHEMBL15459927 0.79 GABRA1 (0.55) MEN1KMT2AMAPTMAPK1HTT
SCHEMBL815323 0.79 MEN1 (0.53) MEN1KMT2AMAPTMAPK1HTT
SCHEMBL15459931 0.79 GABRA1 (0.55) MEN1KMT2AMAPTMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037020-A Supported catalyst, preparation method thereof and application thereof in olefin polymerization 中国石油化工股份有限公司 2026-05-15 — — CN claimed
EP-1133504-B1 METHOD FOR PRODUCING MONOARYLOXY-ANSA-METALLOCENES BASELL POLYOLEFINE GMBH (DE) 2003-03-12 — — EP claimed
US-4360478-A Preparation of α-cyanobenzyl esters SHELL OIL COMPANY (US) 1982-11-23 — — US claimed
US-4153626-A Preparation of α-cyanobenzyl esters SHELL OIL COMPANY (US) 1979-05-08 — — US claimed
CN-122037020-A Supported catalyst, preparation method thereof and application thereof in olefin polymerization 中国石油化工股份有限公司 2026-05-15 — — CN disclosed
CN-118791364-A Cycloparaffin intermediate and preparation method of cycloparaffin 山东百诺医药股份有限公司 2024-10-18 — — CN disclosed
US-12030853-B2 MASP-2 inhibitors and methods of use OMEROS CORPORATION (US) 2024-07-09 — — US disclosed
CN-112679635-B Preparation method of supported metallocene catalyst and catalyst prepared by preparation method 中国石油化工股份有限公司 2024-03-26 — — CN disclosed
US-11858880-B2 Anti-fungals compounds targeting the synthesis of fungal sphingolipids THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2024-01-02 — — US disclosed
US-20230322715-A1 BROAD SPECTRUM ANTI-CANCER COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-10-12 — — US disclosed
US-11773086-B2 Fungal modulators TRUSTEES OF BOSTON UNIVERSITY (US) 2023-10-03 — — US disclosed
US-11773086-B2 Fungal modulators TRUSTEES OF BOSTON UNIVERSITY (US) 2023-10-03 — — US disclosed
US-4324889-A 2,5-Inter-o-phenylene-3,4-dinor-6,9α-epoxy-6β-5-iodo-PGF1 amides THE UPJOHN COMPANY (US) 1982-04-13 — — US disclosed
US-4306075-A Composition and process THE UPJOHN COMPANY (US) 1981-12-15 — — US disclosed
US-4306076-A Inter-phenylene CBA compounds THE UPJOHN COMPANY (US) 1981-12-15 — — US disclosed
US-4289893-A 2,5-Inter-O-phenylene-3,4-dinor-PGF2 compounds THE UPJOHN COMPANY (US) 1981-09-15 — — US disclosed
US-4281113-A 2,5-Inter-o-phenylene-3,4-dinor-6,9α-epoxy-6.beta.-5-iodo-PGF1 compounds THE UPJOHN COMPANY (US) 1981-07-28 — — US disclosed
US-4243592-A THROMBOXANES; PROSTAGLANDINS; ANTIINFLAMMATORY AND BRONCHODILATOR AGENTS; ANTICOAGULANTS THE UPJOHN COMPANY (US) 1981-01-06 — — US disclosed
US-4220796-A 9-Deoxy-9-methylene-5,6-didehydro-PGF1 compounds THE UPJOHN COMPANY (US) 1980-09-02 — — US disclosed
US-4218378-A 11a-Methano-TXA compounds THE UPJOHN COMPANY (US) 1980-08-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11773086-B2 Fungal modulators ABCB11, ABCB1, ABCC1 MEN1 2136/4885KMT2A 4152/4885MAPT 3016/4885
US-11858880-B2 Anti-fungals compounds targeting the synthesis of fungal sphingolipids ERG28, UGCG, DPM1 MEN1 1341/4885KMT2A 3071/4885MAPT 2146/4885
US-20230322715-A1 BROAD SPECTRUM ANTI-CANCER COMPOUNDS YTHDF1, YTHDF3, YTHDF2 MEN1 3143/4885KMT2A 134/4885MAPT 2330/4885
US-12030853-B2 MASP-2 inhibitors and methods of use MASP2, METAP2, SPINT2 MEN1 150/4885KMT2A 2885/4885MAPT 3549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.