Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.52 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28079640 | 0.94 | TSHR (0.60) | TSHRPOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14236838 | 0.93 | TSHR (0.58) | TSHRPOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL19174812 | 0.92 | ALDH1A1 (0.58) | TSHRPOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3542244 | 0.90 | LMNA (0.63) | TSHRPOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL240523 | 0.89 | TSHR (0.63) | TSHRPOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL31229576 | 0.84 | POLB (0.60) | POLBRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL12443203 | 0.82 | LMNA (0.62) | TSHRPOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6458973 | 0.81 | MCHR1 (0.53) | POLB | |
| SCHEMBL6458979 | 0.81 | MCHR1 (0.53) | POLB | |
| SCHEMBL385099 | 0.80 | TSHR (0.68) | TSHRPOLBRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961746-B1 | PHTHALAMIDE DERIVATIVE, AGRICULTURAL OR HORTICULTURAL PESTICIDE, AND USE OF THE PESTICIDE | NIHON NOHYAKU CO LTD (JP) | 2012-03-28 | — | — | EP | disclosed |
| US-7994339-B2 | Phthalamide derivative, agricultural or horticultural pesticide, and use of the pesticide | NIHON NOHYAKU CO., LTD. (JP) | 2011-08-09 | — | — | US | disclosed |
| US-7994339-B2 | Phthalamide derivative, agricultural or horticultural pesticide, and use of the pesticide | NIHON NOHYAKU CO., LTD. (JP) | 2011-08-09 | — | — | US | disclosed |
| US-7994339-B2 | Phthalamide derivative, agricultural or horticultural pesticide, and use of the pesticide | NIHON NOHYAKU CO., LTD. (JP) | 2011-08-09 | — | — | US | disclosed |
| US-20090111861-A1 | Phthalamide Derivative, Agricultural or Horticultural Pesticide, and Use of the Pesticide | NIHON NOHYAKU CO., LTD. (JP) | 2009-04-30 | — | — | US | disclosed |
| US-20090111861-A1 | Phthalamide Derivative, Agricultural or Horticultural Pesticide, and Use of the Pesticide | NIHON NOHYAKU CO., LTD. (JP) | 2009-04-30 | — | — | US | disclosed |
| US-20090111861-A1 | Phthalamide Derivative, Agricultural or Horticultural Pesticide, and Use of the Pesticide | NIHON NOHYAKU CO., LTD. (JP) | 2009-04-30 | — | — | US | disclosed |
| EP-1961746-A1 | PHTHALAMIDE DERIVATIVE, AGRICULTURAL OR HORTICULTURAL PESTICIDE, AND USE OF THE PESTICIDE | Nihon Nohyaku Co., Ltd. (JP) | 2008-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111861-A1 | Phthalamide Derivative, Agricultural or Horticultural Pesticide, and Use of the Pesticide | DDT, HDAC2, HDAC1 | TSHR 2436/4885POLB 4539/4885RAB9A 3650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.