Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446171 | 1.00 | ADRB3 (0.34) | ADRB3ADRB2ADRB1KDM4EAHR | |
| SCHEMBL8446155 | 0.92 | HTR1A (0.35) | ADRB3ADRB2ADRB1KDM4EAHR | |
| SCHEMBL8446154 | 0.92 | HTR1A (0.35) | ADRB3ADRB2ADRB1KDM4EAHR | |
| SCHEMBL2453666 | 0.75 | ADRB2 (0.39) | ADRB3ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL2453671 | 0.75 | ADRB2 (0.39) | ADRB3ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL2452610 | 0.73 | ADRB2 (0.38) | ADRB3ADRB2ADRB1KDM4EAHR | |
| SCHEMBL2452609 | 0.73 | ADRB2 (0.38) | ADRB3ADRB2ADRB1KDM4EAHR | |
| SCHEMBL7535674 | 0.72 | NR1I2 (0.48) | HTR1AADORA3TBXA2RSLC6A2HTR2A | |
| SCHEMBL7535672 | 0.72 | NR1I2 (0.48) | HTR1AADORA3TBXA2RSLC6A2HTR2A | |
| SCHEMBL8883016 | 0.72 | IDO1 (0.43) | ADRB3ADRB2ADRB1KDM4EAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893433-A1 | ALPHA-ALKOXYIMINOBENZYL DERIVATIVES AND AGRICULTURAL CHEMICALS CONTAINING THEM AS ACTIVE INGREDIENTS | SHIONOGI & CO., LTD. (JP) | 1999-01-27 | — | — | EP | disclosed |