SCHEMBL8446273

SCHEMBL8446273

CC(C)CCc1cccc(C(=O)NO)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 7/20 0.52
HDAC8 Q9BY41 6/20 0.52
HDAC1 Q13547 3/20 0.52
HDAC2 Q92769 2/20 0.52
HDAC3 O15379 1/20 0.52
HDAC4 P56524 1/20 0.52
HDAC7 Q8WUI4 1/20 0.52
HDAC10 Q969S8 1/20 0.52
HDAC11 Q96DB2 1/20 0.52
HDAC9 Q9UKV0 1/20 0.52
HDAC5 Q9UQL6 1/20 0.52
MAP1LC3B Q9GZQ8 3/20 0.52
MAP1LC3A Q9H492 3/20 0.52
GAA P10253 1/20 0.49
KMT2A Q03164 1/20 0.49
HSD17B10 Q99714 1/20 0.49
KDM4E B2RXH2 1/20 0.49
EGLN2 Q96KS0 1/20 0.49
SMPD1 P17405 1/20 0.48
HPGD P15428 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14131214 0.88 SLC7A5 (0.57) HDAC6HDAC8MAP1LC3BMAP1LC3AGAA
SCHEMBL1926603 0.82 HDAC2 (0.61) HDAC6HDAC8HDAC2GAAKMT2A
SCHEMBL9013617 0.82 MAP1LC3B (0.48) MAP1LC3BMAP1LC3AGAAKMT2AHSD17B10
SCHEMBL13126937 0.82 MAP1LC3B (0.47) MAP1LC3BMAP1LC3AHPGD
SCHEMBL14473131 0.82 KAT6A (0.58) HDAC6HDAC8HDAC1HDAC2HDAC3
SCHEMBL848969 0.82 FOLH1 (0.56) MAP1LC3BMAP1LC3AHSD17B10KDM4E
SCHEMBL1928098 0.81 NPC1 (0.67) HDAC6HDAC8HDAC1HDAC2HDAC3
SCHEMBL1925403 0.81 CYP4F2 (0.69) MAP1LC3BMAP1LC3AKDM4EHPGD
SCHEMBL24788809 0.81 MAP1LC3B (0.46) MAP1LC3BMAP1LC3AGAAKMT2AHSD17B10
SCHEMBL14131093 0.81 FOLH1 (0.49) MAP1LC3BMAP1LC3AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0513397-B1 BENZOHYDROXIMOYLAZOLE DERIVATIVE, PRODUCTION THEREOF AND INSECTICIDE KUMIAI CHEMICAL INDUSTRY CO (JP) 1999-04-14 EP disclosed
EP-0513397-A1 BENZOHYDROXIMOYLAZOLE DERIVATIVE, PRODUCTION THEREOF AND INSECTICIDE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1992-11-19 EP disclosed