SCHEMBL8446358

SCHEMBL8446358

C[Si](C)(CCCCCCl)O[Si](C)(C)CCCCCCl

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
ALDH1A1 P00352 2/20 0.39
TDP1 Q9NUW8 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8448664 1.00 TSHR (0.39) TSHRALDH1A1TDP1
SCHEMBL8006763 0.97 TSHR (0.35) TSHRALDH1A1TDP1
SCHEMBL1482678 0.89 TSHR (0.33) TSHRALDH1A1TDP1
SCHEMBL11806055 0.82 ALDH1A1 (0.38) TSHRALDH1A1
SCHEMBL17668995 0.82 ALDH1A1 (0.38) TSHRALDH1A1
SCHEMBL17669106 0.82 ALDH1A1 (0.38) TSHRALDH1A1
SCHEMBL9692410 0.82 ALDH1A1 (0.38) TSHRALDH1A1
SCHEMBL31714288 0.82 ALDH1A1 (0.38) TSHRALDH1A1
SCHEMBL17134 0.79 TSHR (0.30) TSHRALDH1A1TDP1
SCHEMBL1585600 0.79 TSHR (0.33) TSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0676437-B1 USE OF POLYCATIONIC POLYMER AS BACTERICIDAL/ALGICIDAL AGENT SAGAMI CHEM RES (JP) 1999-09-08 EP disclosed
US-5616317-A HETEROCYCLIC NITROGEN POLYMER SAGAMI CHEMICAL RESEARCH CENTER (JP) 1997-04-01 US disclosed
EP-0676437-A1 POLYCATIONIC POLYMER AND POLYCATIONIC BACTERICIDAL/ALGICIDAL AGENT SAGAMI CHEMICAL RESEARCH CENTER (JP) 1995-10-11 EP disclosed