Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.51 |
| ▸ | ACE | P12821 | 5/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ECE1 | P42892 | 2/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446405 | 0.90 | MME (0.48) | MMEACECTSBFDFT1CTSL | |
| SCHEMBL8450803 | 0.90 | MME (0.48) | MMEACECTSBFDFT1CTSL | |
| SCHEMBL8446471 | 0.88 | MME (0.47) | MMEACECTSBFDFT1CTSL | |
| SCHEMBL8450247 | 0.88 | MME (0.47) | MMEACECTSBFDFT1CTSL | |
| SCHEMBL8451198 | 0.88 | MME (0.48) | MMEACECTSBFDFT1CTSL | |
| SCHEMBL7565205 | 0.85 | MME (0.70) | MMEACECTSBACE2 | |
| SCHEMBL8447179 | 0.85 | MME (0.55) | MMEACECTSBFDFT1 | |
| SCHEMBL7565208 | 0.85 | MME (0.70) | MMEACECTSBACE2 | |
| SCHEMBL8449676 | 0.84 | MME (0.48) | MMEACECTSBFDFT1ACACB | |
| SCHEMBL8446381 | 0.84 | MME (0.62) | MMEACECTSBCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |