Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.47 |
| ▸ | ACE | P12821 | 5/20 | 0.47 |
| ▸ | MMP3 | P08254 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568400 | 0.96 | MME (0.52) | MMEACEMMP3MMP2PPARG | |
| SCHEMBL7568408 | 0.96 | MME (0.52) | MMEACEMMP3MMP2PPARG | |
| SCHEMBL8452660 | 0.93 | MME (0.52) | MMEACEMMP3TACR1CTSB | |
| SCHEMBL8450243 | 0.90 | MME (0.57) | MMEACEMMP3TACR1CTSB | |
| SCHEMBL8447122 | 0.90 | MME (0.57) | MMEACEMMP3TACR1CTSB | |
| SCHEMBL27441332 | 0.89 | MME (0.57) | MMEACEPPARGPPARATACR1 | |
| SCHEMBL8446385 | 0.88 | MME (0.60) | MMEACEMMP2TACR1CTSB | |
| SCHEMBL7570079 | 0.88 | MME (0.58) | MMEACEMMP3CTSB | |
| SCHEMBL8450109 | 0.88 | MME (0.52) | MMEACEMMP3MMP2TACR1 | |
| SCHEMBL7569082 | 0.88 | MME (0.57) | MMEACEMMP3MMP2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |