Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 8/20 | 0.64 |
| ▸ | NT5C2 | P49902 | 2/20 | 0.56 |
| ▸ | NT5E | P21589 | 1/20 | 0.54 |
| ▸ | STAT3 | P40763 | 3/20 | 0.52 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121393 | 0.84 | STAT3 (0.69) | BRD4NT5C2NT5ESTAT3CREBBP | |
| SCHEMBL5694052 | 0.84 | BRD4 (0.67) | BRD4NT5C2NT5ESTAT3CREBBP | |
| SCHEMBL475842 | 0.83 | BRD4 (0.66) | BRD4NT5C2NT5ESTAT3CREBBP | |
| SCHEMBL5694204 | 0.83 | BRD4 (0.66) | BRD4NT5C2NT5ESTAT3CREBBP | |
| SCHEMBL28472898 | 0.82 | BRD4 (0.46) | BRD4NT5C2NT5ESTAT3CREBBP | |
| SCHEMBL8362516 | 0.81 | BRD4 (0.45) | BRD4NT5C2NT5ESTAT3BTK | |
| SCHEMBL10432005 | 0.80 | BRD4 (0.62) | BRD4NT5C2NT5ESTAT3CREBBP | |
| SCHEMBL23124 | 0.79 | BRD4 (1.00) | BRD4NT5C2NT5ECREBBPNPC1 | |
| SCHEMBL134909 | 0.79 | PDPK1 (0.49) | BRD4STAT3NPC1RAB9APOLB | |
| SCHEMBL29514799 | 0.79 | BRD4 (1.00) | BRD4NT5C2NT5ECREBBPNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997014709-A1 | ANTISENSE OLIGOMERS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-04-24 | — | — | WO | claimed |
| JP-60199899-A | — | — | None | — | — | JP | disclosed |
| EP-0705264-B1 | CARBO-ACYCLIC NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AND ANTINEOPLASTIC AGENTS | MERRELL PHARMA INC (US) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997014709-A1 | ANTISENSE OLIGOMERS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-04-24 | — | — | WO | disclosed |
| WO-1995000515-A1 | CARBO-ACYCLIC NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AND ANTINEOPLASTIC AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1995-01-05 | — | — | WO | disclosed |
| JP-S60199899-A | NUCLEOSIDE 3'-PHOSPHOTRIESTER DERIVATIVE | FUJIREBIO INC | 1985-10-09 | — | — | JP | disclosed |