Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 8/20 | 0.62 |
| ▸ | NT5C2 | P49902 | 2/20 | 0.54 |
| ▸ | STAT3 | P40763 | 3/20 | 0.53 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5694204 | 0.84 | BRD4 (0.66) | BRD4NT5C2STAT3NT5ECREBBP | |
| SCHEMBL5694052 | 0.82 | BRD4 (0.67) | BRD4NT5C2STAT3NT5ECREBBP | |
| SCHEMBL8121393 | 0.82 | STAT3 (0.69) | BRD4NT5C2STAT3NT5ECREBBP | |
| SCHEMBL2514195 | 0.81 | BRD4 (0.47) | BRD4NT5C2STAT3NT5E | |
| SCHEMBL475842 | 0.81 | BRD4 (0.66) | BRD4NT5C2STAT3NT5ECREBBP | |
| SCHEMBL8446397 | 0.80 | BRD4 (0.64) | BRD4NT5C2STAT3NT5ECREBBP | |
| SCHEMBL29514799 | 0.77 | BRD4 (1.00) | BRD4NT5C2NT5ECREBBPBTK | |
| SCHEMBL23124 | 0.77 | BRD4 (1.00) | BRD4NT5C2NT5ECREBBPBTK | |
| SCHEMBL6463477 | 0.76 | BRD4 (0.92) | BRD4NT5C2NT5ECREBBPBTK | |
| SCHEMBL8381776 | 0.76 | BRD4 (0.97) | BRD4NT5C2NT5ECREBBPBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102424698-A | Modified 2' and 3' -nucleoside produgs for treating flaviridae infections | CENTRE NAT RECH SCIENT (FR) | 2012-04-25 | — | — | CN | disclosed |
| EP-0391411-A2 | 3'-Substituted methyl nucleosides as antiviral agents | Bristol-Myers Squibb Company (US) | 1990-10-10 | — | — | EP | disclosed |