SCHEMBL23124

SCHEMBL23124

O=C(Nc1ncnc2nc[nH]c12)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 13/20 1.00
NT5C2 P49902 2/20 0.85
NT5E P21589 1/20 0.81
CREBBP Q92793 1/20 0.70
TOP2A P11388 2/20 0.60
BTK Q06187 1/20 0.60
BRAF P15056 1/20 0.58
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29514799 1.00 BRD4 (1.00) BRD4NT5C2NT5ECREBBPTOP2A
SCHEMBL8381776 0.99 BRD4 (0.97) BRD4NT5C2NT5ECREBBPTOP2A
SCHEMBL6463477 0.96 BRD4 (0.92) BRD4NT5C2NT5ECREBBPTOP2A
SCHEMBL9230081 0.83 BRD4 (1.00) BRD4NT5C2NT5ECREBBPNPC1
SCHEMBL23683051 0.82 CREBBP (1.00) BRD4NT5C2NT5ECREBBPTOP2A
SCHEMBL3038563 0.82 NPC1 (0.76) BRD4NT5C2NT5ECREBBPTOP2A
SCHEMBL22118772 0.82 BRD4 (0.68) BRD4NT5C2NT5ECREBBPTOP2A
SCHEMBL10644711 0.81 BRD4 (0.68) BRD4NT5C2NT5ECREBBPTOP2A
SCHEMBL5694052 0.81 BRD4 (0.67) BRD4NT5C2NT5ECREBBPBTK
SCHEMBL8121393 0.81 STAT3 (0.69) BRD4NT5C2NT5ECREBBPBTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2007 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
US-12428441-B2 Modified nucleoside phosphoramidites Janssen Biopharma, Inc. (US) 2025-09-30 US claimed
EP-4484439-B1 6'-CYANO-MODIFIED LOCKED NUCLEOSIDE, NUCLEOTIDE, AND NUCLEIC ACID POLYMER ACAD OF MILITARY MEDICAL SCIENCES (CN) 2025-09-17 EP claimed
EP-4606903-A1 METHOD FOR ENZYMATIC SYNTHESIS OF NUCLEOSIDE CONTAINING PROTECTING GROUP, AND COMPOSITION Asymchem Life Science (Tianjin) Co., Ltd (CN) 2025-08-27 EP claimed
EP-4560315-A2 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES F. Hoffmann-La Roche AG (CH) 2025-05-28 EP claimed
EP-3980554-B1 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES HOFFMANN LA ROCHE (CH) 2025-03-26 EP claimed
EP-4484439-A1 6'-CYANO-MODIFIED LOCKED NUCLEOSIDE, NUCLEOTIDE, AND NUCLEIC ACID POLYMER Academy of Military Medical Sciences (CN) 2025-01-01 EP claimed
WO-2024234728-A1 6'-CYANO-MODIFIED LOCKED NUCLEOSIDE, NUCLEOTIDE, AND NUCLEIC ACID POLYMER 中国人民解放军军事科学院军事医学研究院 2024-11-21 WO claimed
CN-118931997-A Method for synthesizing adenosine and/or uridine by three-enzyme cascade catalysis 上海飞腾医药科技有限公司 2024-11-12 CN claimed
US-20240309040-A1 Modified Nucleoside Phosphoramidites Janssen Biopharma, Inc. (US) 2024-09-19 US claimed
EP-0644196-A1 TTTr as a protecting group in nucleotide synthesis CIBA-GEIGY AG (CH) 1995-03-22 EP claimed
EP-0626387-A1 Nucleosides and oligonucleotides with 2'-ether groups CIBA-GEIGY AG (CH) 1994-11-30 EP claimed
US-5332814-A Process for the preparation of carbacyclic nucleosides, and intermediates CIBA-GEIGY CORPORATION (US) 1994-07-26 US claimed
US-5319080-A Antiviral agents CIBA-GEIGY CORPORATION (US) 1994-06-07 US claimed
EP-0577558-A2 Carbocyclic nucleosides having bicyclic rings, oligonucleotides therefrom, process for their preparation, their use and intermediates CIBA-GEIGY AG (CH) 1994-01-05 EP claimed
EP-0542681-A1 Process for the preparation of carbocyclic nucleosides and its intermediates CIBA-GEIGY AG (CH) 1993-05-19 EP claimed
EP-0538194-A1 Bicyclic nucleosides, oligonucleotides, their method of preparation and intermediates therein CIBA-GEIGY AG (CH) 1993-04-21 EP claimed
WO-1992001700-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1992-02-06 WO claimed
EP-0428109-A2 Deoxyfluoronucleoside process Bristol-Myers Squibb Company (US) 1991-05-22 EP claimed
EP-0064796-B1 PHOSPHORYLATING AGENT AND PROCESS FOR THE PHOSPHORYLATION OF ORGANIC HYDROXYL COMPOUNDS UNILEVER N.V. (NL) 1985-05-15 EP claimed