Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.55 |
| ▸ | ACE | P12821 | 6/20 | 0.55 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566348 | 0.93 | ACE (0.65) | MMEACECTSBCTSSCTSK | |
| SCHEMBL8451289 | 0.91 | MME (0.52) | MMEACECTSBCTSSCTSK | |
| SCHEMBL8446481 | 0.91 | MME (0.62) | MMEACETACR1CTSBCTSS | |
| SCHEMBL8446416 | 0.90 | MME (0.55) | MMEACETACR1CTSBCTSS | |
| SCHEMBL8447138 | 0.89 | MME (0.58) | MMEACETACR1CTSBCTSS | |
| SCHEMBL8447214 | 0.89 | MME (0.55) | MMEACECTSBCTSSCTSL | |
| SCHEMBL8449480 | 0.88 | MME (0.53) | MMEACETACR1CTSBCTSS | |
| SCHEMBL8446417 | 0.87 | MME (0.52) | MMEACECTSBMMP1MMP3 | |
| SCHEMBL8449459 | 0.87 | MME (0.52) | MMEACECTSBMMP1MMP3 | |
| SCHEMBL8450109 | 0.87 | MME (0.52) | MMEACETACR1CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |