Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768634 | 0.87 | DRD2 (0.75) | DRD2 | |
| SCHEMBL8823630 | 0.86 | DRD2 (0.58) | DRD2 | |
| Hydrochloric Acid SCHEMBL8823814 | 0.86 | DRD2 (0.77) | DRD2 | |
| SCHEMBL8453594 | 0.86 | HTR1A (0.63) | DRD2 | |
| SCHEMBL27295529 | 0.86 | DRD2 (0.60) | DRD2 | |
| Hydrochloric Acid SCHEMBL8823831 | 0.85 | DRD2 (0.59) | DRD2 | |
| SCHEMBL8823564 | 0.85 | DRD2 (0.59) | DRD2 | |
| SCHEMBL8823668 | 0.84 | DRD2 (0.64) | DRD2 | |
| SCHEMBL8823844 | 0.84 | DRD2 (0.58) | DRD2 | |
| SCHEMBL8823741 | 0.84 | DRD2 (0.58) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2879972-B2 | — | — | 1999-04-05 | — | — | JP | claimed |
| EP-0460169-B1 | NEW CHROMAN AND THIOCHROMAN DERIVATIVES | ASTRA AB (SE) | 1996-06-05 | — | — | EP | claimed |
| WO-1991009853-A1 | NEW CHROMAN AND THIOCHROMAN DERIVATIVES | AKTIEBOLAGET ASTRA (SE) | 1991-07-11 | — | — | WO | claimed |
| US-5656657-A | Chroman derivatives | ASTRA AKTIEBOLAG (SE) | 1997-08-12 | — | — | US | disclosed |
| US-5656658-A | Method for the treatment of anxiety | ASTRA AKTIEBOLAG (SE) | 1997-08-12 | — | — | US | disclosed |
| US-5650524-A | Process for preparing (R)-3-amino-5-methoxychroman | ASTRA AKTIEBOLAG (SE) | 1997-07-22 | — | — | US | disclosed |
| US-5646309-A | Intermediates in the synthesis of chroman derivatives | ASTRA AKTIEBOLAG (SE) | 1997-07-08 | — | — | US | disclosed |
| US-5641807-A | Method for the treatment of depression | ASTRA AKTIEBOLAG (SE) | 1997-06-24 | — | — | US | disclosed |
| US-5639772-A | Chroman derivatives | ASTRA AKTIEBOLAG (SE) | 1997-06-17 | — | — | US | disclosed |
| US-5639784-A | ADMINISTERING 3-AMINO-5-CARBAMOYL-CHROMENES AND DERIVATIVES | ASTRA AKTIEBOLAG (SE) | 1997-06-17 | — | — | US | disclosed |
| EP-0460169-B1 | NEW CHROMAN AND THIOCHROMAN DERIVATIVES | ASTRA AB (SE) | 1996-06-05 | — | — | EP | disclosed |
| US-5500425-A | Chroman derivatives and a method of treating 5-HT mediated disorders | AKTIEBOLAGET ASTRA (SE) | 1996-03-19 | — | — | US | disclosed |
| US-5420151-A | Chroman derivatives | AKTIEBOLAGET ASTRA (SE) | 1995-05-30 | — | — | US | disclosed |
| EP-0460169-A1 | NEW CHROMAN AND THIOCHROMAN DERIVATIVES. | ASTRA AB (SE) | 1991-12-11 | — | — | EP | disclosed |
| WO-1991009853-A1 | NEW CHROMAN AND THIOCHROMAN DERIVATIVES | AKTIEBOLAGET ASTRA (SE) | 1991-07-11 | — | — | WO | disclosed |