Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ATP4A | P20648 | 1/20 | 0.46 |
| ▸ | ATP4B | P51164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844711 | 0.93 | SMN1; SMN2 (0.55) | SMN1; SMN2USP2ATP4AATP4BTSHR | |
| SCHEMBL11995138 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2USP2TSHRMAPTPDE10A | |
| SCHEMBL103809 | 0.82 | RAB9A (0.60) | SMN1; SMN2USP2MAPTPDE10ANPC1 | |
| SCHEMBL16465691 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2USP2TSHRMAPTPDE10A | |
| SCHEMBL6865472 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2USP2TSHRMAPTPDE10A | |
| SCHEMBL3746825 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2USP2TSHRMAPTPDE10A | |
| SCHEMBL31248989 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2USP2TSHRMAPTPDE10A | |
| Hydrochloric Acid SCHEMBL6000086 | 0.80 | RAB9A (0.58) | SMN1; SMN2USP2MAPTPDE10ANPC1 | |
| SCHEMBL29087537 | 0.78 | MAPT (0.58) | SMN1; SMN2USP2TSHRMAPTPDE10A | |
| SCHEMBL6868621 | 0.77 | SMN1; SMN2 (0.58) | SMN1; SMN2USP2TSHRMAPTPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2436750-A2 | Ligand exchange thermochromic, (LETC), systems | Pleotint, L.L.C. (US) | 2012-04-04 | — | — | EP | disclosed |
| EP-2434000-A2 | Ligand exchange thermochromic, (LETC), systems | Pleotint, L.L.C. (US) | 2012-03-28 | — | — | EP | disclosed |