SCHEMBL103809

SCHEMBL103809

Cn1c(CCl)nc2ccccc21

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 0.60
NPC1 O15118 7/20 0.60
SMN1; SMN2 Q16637 6/20 0.60
LMNA P02545 3/20 0.60
KDM4E B2RXH2 1/20 0.58
POLB P06746 1/20 0.58
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
PKM P14618 3/20 0.57
MAPT P10636 2/20 0.57
HDAC6 Q9UBN7 1/20 0.57
TP53 P04637 1/20 0.56
MAPK1 P28482 1/20 0.56
PDE10A Q9Y233 2/20 0.55
GAA P10253 1/20 0.55
CYP2D6 P10635 1/20 0.55
USP2 O75604 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6000086 0.98 RAB9A (0.58) RAB9ANPC1SMN1; SMN2LMNAKDM4E
SCHEMBL1059693 0.84 RAB9A (0.64) RAB9ANPC1SMN1; SMN2LMNAKDM4E
SCHEMBL10349948 0.84 NPC1 (0.57) RAB9ANPC1SMN1; SMN2LMNAKDM4E
SCHEMBL757031 0.82 RAB9A (0.62) RAB9ANPC1SMN1; SMN2LMNAKDM4E
SCHEMBL30037937 0.82 RAB9A (0.62) RAB9ANPC1SMN1; SMN2LMNAKDM4E
SCHEMBL844728 0.82 SMN1; SMN2 (0.49) RAB9ANPC1SMN1; SMN2LMNAKDM4E
SCHEMBL285358 0.81 RAB9A (0.60) RAB9ANPC1SMN1; SMN2LMNAKDM4E
SCHEMBL104281 0.81 HDAC6 (0.61) RAB9ANPC1SMN1; SMN2LMNAKDM4E
SCHEMBL243922 0.81 LMNA (0.61) RAB9ANPC1SMN1; SMN2LMNAKDM4E
SCHEMBL2929122 0.81 MAPT (0.66) RAB9ANPC1SMN1; SMN2LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015339-A1 CALIX[4]ARENES WITH HIGH ANTICANCER ACTIVITY UNIVERSITE GRENOBLE ALPES (FR) 2026-01-15 US disclosed
EP-4655285-A1 CALIX[4]ARENES WITH HIGH ANTICANCER ACTIVITY Université Grenoble Alpes (FR) 2025-12-03 EP disclosed
EP-4249470-B1 METHOD FOR PREPARING ALPHA-AMINO ACIDS PHILIPPS UNIV MARBURG (DE) 2024-11-13 EP disclosed
US-20240368133-A1 Compounds for the Treatment of Pain, in Particular, Neuropathic Pain, and/or Other Diseases or Disorders that are Associated with AT2R and/or AT2R Mediated Signaling CONFO THERAPEUTICS N.V. (BE) 2024-11-07 US disclosed
CN-114507246-B Benzimidazole substituted amino phenol oxygen zinc halide, and preparation method and application thereof 华东理工大学 2024-09-24 CN disclosed
CN-118684676-A Heterocyclic compound, and preparation method and application thereof 上海济煜医药科技有限公司 2024-09-24 CN disclosed
WO-2024156819-A1 CALIX[4]ARENES WITH HIGH ANTICANCER ACTIVITY UNIVERSITE GRENOBLE ALPES (FR) 2024-08-02 WO disclosed
EP-4406939-A1 CALIX[4]ARENES WITH HIGH ANTICANCER ACTIVITY Université Grenoble Alpes (FR) 2024-07-31 EP disclosed
CN-118159530-A Compounds for the treatment of pain, in particular neuropathic pain and/or other diseases or disorders associated with AT2R and/or AT2R mediated signalling 康福治疗有限公司 2024-06-07 CN disclosed
US-20240180907-A1 ALDOSE REDUCTASE INHIBITORS AND USES THEREOF THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2024-06-06 US disclosed
CN-86108308-A Heterocycle oxo-2 guanidine-acetic acid 1987-07-15 CN disclosed
EP-0226342-A1 5-Phenyl-2-oxazole derivatives as anti-inflammatory/antiallergic agents AMERICAN HOME PRODUCTS CORPORATION (US) 1987-06-24 EP disclosed
EP-0222576-A2 Heterocyclic oxophthalazinyl acetic acids PFIZER INC. (US) 1987-05-20 EP disclosed
EP-0014411-B1 PROCESS FOR THE PREPARATION OF BENZIMIDAZOLYLBENZOFURANS BAYER AG (DE) 1981-10-07 EP disclosed
US-4268670-A Process for the preparation of benzimidazolylbenzofuranes BAYER AKTIENGESELLSCHAFT (DE) 1981-05-19 US disclosed
US-4251619-A Process for forming photo-polymeric image KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-02-17 US disclosed
EP-0014411-A1 Process for the preparation of benzimidazolylbenzofurans BAYER AG (DE) 1980-08-20 EP disclosed
EP-0012291-A1 Process for the preparation of benzimidazolyl benzofuranes BAYER AG (DE) 1980-06-25 EP disclosed
US-4140852-A WHITENING BAYER AKTIENGESELLSCHAFT (DE) 1979-02-20 US disclosed
US-3957513-A Method of free radical photography utilizing a short light flash for exposure ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015339-A1 CALIX[4]ARENES WITH HIGH ANTICANCER ACTIVITY CBR1, CYP4X1, CBR3 RAB9A 3347/4885NPC1 289/4885SMN1; SMN2 2691/4885
US-20240180907-A1 ALDOSE REDUCTASE INHIBITORS AND USES THEREOF ALDOA, AKR1B1, AKR1C2 RAB9A 3696/4885NPC1 747/4885SMN1; SMN2 2204/4885
US-20240368133-A1 Compounds for the Treatment of Pain, in Particular, Neuropathic Pain, and/or Other Diseases or Disorders that are Associated with AT2R and/or AT2R Mediated Signaling AGTR2, AGTR1, OPRL1 RAB9A 2496/4885NPC1 1380/4885SMN1; SMN2 1716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.