Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | UGCG | Q16739 | 2/20 | 0.35 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257357 | 1.00 | TACR1 (0.43) | TACR1TSHRKDM4EPOLBGBA1 | |
| SCHEMBL9264621 | 1.00 | TACR1 (0.43) | TACR1TSHRKDM4EPOLBGBA1 | |
| SCHEMBL9264627 | 1.00 | TACR1 (0.43) | TACR1TSHRKDM4EPOLBGBA1 | |
| SCHEMBL9618014 | 0.75 | TSHR (0.50) | TACR1TSHRKDM4EPOLBSLC6A4 | |
| SCHEMBL30706597 | 0.74 | TSHR (0.38) | TSHRKDM4EPOLBSLC6A2CHRM3 | |
| SCHEMBL25260175 | 0.72 | CYP3A4 (0.36) | TACR1TSHRPOLB | |
| SCHEMBL25831069 | 0.72 | CYP3A4 (0.36) | TACR1TSHRPOLB | |
| SCHEMBL3488328 | 0.71 | TSHR (0.50) | TACR1TSHRKDM4EPOLBSLC6A2 | |
| SCHEMBL21340791 | 0.71 | TSHR (0.45) | TACR1TSHRKDM4EPOLBGBA1 | |
| SCHEMBL1857389 | 0.70 | TSHR (0.48) | TACR1TSHRKDM4EPOLBGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502690-B1 | Cyclopropane derivative | AJINOMOTO KK (JP) | 1999-12-01 | — | — | EP | disclosed |
| US-5449840-A | Viricides | AJINOMOTO CO., INC. (JP) | 1995-09-12 | — | — | US | disclosed |
| US-5342840-A | Viricides | AJINOMOTO CO., INC. (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0502690-A2 | Cyclopropane derivative | Ajinomoto Co., Inc. (JP) | 1992-09-09 | — | — | EP | disclosed |