Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 7/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL763932 | 0.80 | TSHR (0.48) | TSHRTACR1IDO1AGXTKDM1A | |
| SCHEMBL1863524 | 0.80 | TSHR (0.48) | TSHRTACR1IDO1AGXTKDM1A | |
| SCHEMBL1863521 | 0.80 | TSHR (0.48) | TSHRTACR1IDO1AGXTKDM1A | |
| SCHEMBL9257357 | 0.75 | TACR1 (0.43) | TSHRTACR1KDM4EPOLBSLC6A4 | |
| SCHEMBL9264627 | 0.75 | TACR1 (0.43) | TSHRTACR1KDM4EPOLBSLC6A4 | |
| SCHEMBL8447457 | 0.75 | TACR1 (0.43) | TSHRTACR1KDM4EPOLBSLC6A4 | |
| SCHEMBL9264621 | 0.75 | TACR1 (0.43) | TSHRTACR1KDM4EPOLBSLC6A4 | |
| SCHEMBL4153126 | 0.73 | MAOA (0.55) | TSHRTACR1IDO1AGXTKDM4E | |
| SCHEMBL763893 | 0.73 | TSHR (0.48) | TSHRTACR1IDO1KDM4EPOLB | |
| SCHEMBL1857390 | 0.73 | TSHR (0.48) | TSHRTACR1IDO1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4283545-A | — | — | None | — | — | JP | disclosed |
| JP-H04283545-A | NEW CYCLOPROPANE DERIVATIVE | NIPPON KAYAKU CO LTD | 1992-10-08 | — | — | JP | disclosed |