Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.44 |
| ▸ | ACE | P12821 | 6/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | GPR88 | Q9GZN0 | 3/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8452086 | 0.89 | MME (0.46) | MMEACEGPR88MMP8HSD17B10 | |
| SCHEMBL8447886 | 0.89 | MME (0.56) | MMEACECASRGPR88CTSB | |
| SCHEMBL8447834 | 0.81 | CYP26A1 (0.45) | MMEACEPOLB | |
| SCHEMBL8451866 | 0.80 | MME (0.50) | MMEACEPOLB | |
| SCHEMBL8452846 | 0.79 | POLB (0.43) | MMEACEGPR88POLB | |
| SCHEMBL8447801 | 0.79 | MME (0.52) | MMEACEPOLB | |
| SCHEMBL8447781 | 0.79 | FFAR1 (0.42) | MMEACEPOLB | |
| SCHEMBL8447608 | 0.78 | MME (0.47) | MMEACEGPR88CTSBHSD17B10 | |
| SCHEMBL8447368 | 0.77 | MME (0.58) | MMEACE | |
| SCHEMBL8032958 | 0.77 | MME (0.58) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891912-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |