Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.47 |
| ▸ | ACE | P12821 | 6/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8451407 | 0.94 | MME (0.53) | MMEACECTSBGPR88PTGES | |
| SCHEMBL8452956 | 0.93 | MME (0.43) | MMEACECTSBSMN1; SMN2GPR88 | |
| SCHEMBL8452082 | 0.90 | CYP26A1 (0.44) | MMEACECTSBPTGES | |
| SCHEMBL8448729 | 0.89 | MME (0.52) | MMEACECTSBCASP1PTGES | |
| SCHEMBL8452086 | 0.89 | MME (0.46) | MMEACESMN1; SMN2GPR88HSD17B10 | |
| SCHEMBL8452366 | 0.88 | MME (0.46) | MMEACECTSBSMN1; SMN2GPR88 | |
| SCHEMBL8454177 | 0.87 | MME (0.43) | MMEACECTSB | |
| SCHEMBL8447368 | 0.86 | MME (0.58) | MMEACESMN1; SMN2 | |
| SCHEMBL8452362 | 0.85 | MME (0.51) | MMEACECTSBCASP1 | |
| SCHEMBL8453402 | 0.84 | MME (0.47) | MMEACESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891912-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |