Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.46 |
| ▸ | ACE | P12821 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8447834 | 0.92 | CYP26A1 (0.45) | MMEACESMN1; SMN2CYP26A1ALDH1A1 | |
| SCHEMBL8451866 | 0.91 | MME (0.50) | MMEACESMN1; SMN2CYP26A1NPSR1 | |
| SCHEMBL8452846 | 0.89 | POLB (0.43) | MMEACESMN1; SMN2CYP26A1ALDH1A1 | |
| SCHEMBL8447608 | 0.89 | MME (0.47) | MMEACESMN1; SMN2HSD17B10GPR88 | |
| SCHEMBL8447809 | 0.89 | MME (0.44) | MMEACEMMP8HSD17B10GPR88 | |
| SCHEMBL8447781 | 0.89 | FFAR1 (0.42) | MMEACESMN1; SMN2CYP26A1KMT2A | |
| SCHEMBL8447801 | 0.89 | MME (0.52) | MMEACESMN1; SMN2 | |
| SCHEMBL8447368 | 0.88 | MME (0.58) | MMEACESMN1; SMN2CYP26A1ALDH1A1 | |
| SCHEMBL8453232 | 0.87 | ALDH1A1 (0.43) | MMEACECYP26A1ALDH1A1KDM4E | |
| SCHEMBL8453402 | 0.86 | MME (0.47) | MMEACESMN1; SMN2CYP26A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891912-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |