Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448203 | 0.75 | ALDH1A1 (0.31) | — | |
| SCHEMBL13574820 | 0.71 | — | — | |
| SCHEMBL550353 | 0.71 | — | — | |
| SCHEMBL20880240 | 0.70 | — | — | |
| SCHEMBL22723764 | 0.70 | — | — | |
| SCHEMBL8445941 | 0.68 | — | — | |
| SCHEMBL8448155 | 0.67 | MAPT (0.52) | — | |
| SCHEMBL21610741 | 0.67 | — | — | |
| SCHEMBL10442596 | 0.66 | HCAR2 (0.46) | HCAR2AOC3 | |
| SCHEMBL903234 | 0.65 | HDAC1 (0.38) | HCAR2HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942909-A1 | BICYCLIC AMINE DERIVATIVES | ZENECA LIMITED (GB) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998022463-A1 | BICYCLIC AMINE DERIVATIVES | ZENECA LIMITED (GB) | 1998-05-28 | — | — | WO | disclosed |