Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.52 |
| ▸ | TDO2 | P48775 | 3/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | PNMT | P11086 | 1/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ACP3 | P15309 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464360 | 0.87 | IDO1 (0.61) | IDO1TDO2CES2PNMTNPSR1 | |
| SCHEMBL8410943 | 0.87 | IDO1 (0.61) | IDO1TDO2CES2PNMTNPSR1 | |
| SCHEMBL8460159 | 0.87 | IDO1 (0.61) | IDO1TDO2CES2PNMTNPSR1 | |
| SCHEMBL2166743 | 0.81 | CES2 (0.54) | CES2PNMTPPARGNPSR1ACP3 | |
| SCHEMBL514285 | 0.77 | EPHX1 (0.49) | IDO1TDO2CES2PNMTADAMTS4 | |
| SCHEMBL1760202 | 0.76 | AKR1C3 (0.66) | CES2PNMTNPSR1ACP3KDM4E | |
| SCHEMBL1993610 | 0.76 | AKR1C3 (0.66) | CES2PNMTNPSR1ACP3KDM4E | |
| SCHEMBL3077103 | 0.76 | CES2 (0.50) | IDO1TDO2CES2PNMTADAMTS4 | |
| SCHEMBL14983791 | 0.75 | CES2 (0.53) | IDO1TDO2CES2PNMTADAMTS4 | |
| SCHEMBL8410668 | 0.75 | NPSR1 (0.50) | IDO1TDO2CES2PNMTADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11322693-A | — | — | None | — | — | JP | disclosed |
| JP-H11322693-A | PRODUCTION OF OPTICALLY ACTIVE METHOXYIMINOACETAMIDE DERIVATIVE | MITSUBISHI CHEMICAL CORP | 1999-11-24 | — | — | JP | disclosed |