Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009498 | 0.81 | MAOA (0.49) | MAOBMAOACARM1PRMT6 | |
| SCHEMBL14862904 | 0.81 | MAOB (0.55) | MAOB | |
| SCHEMBL2382152 | 0.81 | CYP2C9 (0.50) | MAOBMAOAGPR84 | |
| SCHEMBL11058080 | 0.81 | MAOB (0.57) | MAOBMAOAGPR84CA2LPL | |
| SCHEMBL11058086 | 0.81 | MAOB (0.57) | MAOBMAOAGPR84CA2LPL | |
| SCHEMBL10697228 | 0.79 | MAOB (0.55) | MAOBMAOALPLLIPG | |
| SCHEMBL9419274 | 0.79 | ESR2 (0.55) | — | |
| SCHEMBL9457804 | 0.78 | MAOA (0.56) | MAOBMAOAGPR84DDB1CRBN | |
| SCHEMBL8455463 | 0.78 | NAAA (0.38) | DDB1CRBN | |
| SCHEMBL27540930 | 0.78 | PTGER4 (0.46) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858275-A | Chlorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| CN-1158601-A | Chlorobenzene derivatives and liquid crystal compositions containing the same | CHISSO CORP (JP) | 1997-09-03 | — | — | CN | disclosed |
| EP-0785179-A1 | CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |
| EP-0362318-B1 | 2,3-DIFLUOROBIPHENYLS | MERCK PATENT GmbH (DE) | 1993-08-04 | — | — | EP | disclosed |
| US-5204019-A | Liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-20 | — | — | US | disclosed |
| EP-0362318-A1 | 2,3-DIFLUOROBIPHENYLS. | MERCK PATENT GMBH (DE) | 1990-04-11 | — | — | EP | disclosed |
| WO-1989008687-A1 | 2,3-DIFLUOROBIPHENYLS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |