2,5-Xylidine

2,5-Xylidine

SCHEMBL8448393

Cc1ccc(C)c(N)c1.Cc1cccc(N)c1C

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.68
TDP1 Q9NUW8 4/20 0.68
CYP3A4 P08684 5/20 0.50
TSHR P16473 1/20 0.50
PIK3CA P42336 1/20 0.50
ALOX15 P16050 2/20 0.46
TP53 P04637 1/20 0.46
THRB P10828 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CD44 P16070 1/20 0.45
CASP1 P29466 1/20 0.45
HSD17B10 Q99714 2/20 0.42
CA1 P00915 1/20 0.41
CYP1A2 P05177 2/20 0.39
CYP2A6 P11509 1/20 0.39
MAPT P10636 1/20 0.38
GAA P10253 2/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,5-Xylidine SCHEMBL9751765 0.96 ALDH1A1 (0.63) ALDH1A1TDP1CYP3A4TSHRPIK3CA
2,5-Xylidine SCHEMBL27949130 0.85 TDP1 (0.77) ALDH1A1TDP1CYP3A4ALOX15TP53
2,5-Xylidine SCHEMBL11124717 0.85 TDP1 (0.77) ALDH1A1TDP1CYP3A4TSHRALOX15
SCHEMBL10830774 0.84 CYP3A4 (0.50) ALDH1A1TDP1CYP3A4TSHRPIK3CA
SCHEMBL15024 0.82
SCHEMBL29440219 0.82
2,5-Xylidine SCHEMBL70824 0.82
SCHEMBL28788726 0.82 CYP3A4 (0.72) ALDH1A1TDP1CYP3A4TSHRPIK3CA
2,5-Xylidine SCHEMBL33981 0.82 ALDH1A1 (0.46) ALDH1A1TDP1CYP3A4TSHRPIK3CA
Hydrochloric Acid SCHEMBL2188812 0.80 CYP3A4 (0.68) ALDH1A1TDP1CYP3A4TSHRPIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5919982-A Process and apparatus for the removal of aromatic amines from soil and water HER MAJESTY THE QUEEN IN RIGHT OF CANADA, AS REPRESENTED BY ENVIRONMENT (CA) 1999-07-06 US disclosed
WO-1997046331-A1 PROCESS AND APPARATUS FOR THE REMOVAL OF AROMATIC AMINES FROM SOIL AND WATER HER MAJESTY IN RIGHT OF CANADA, represented by ENVIRONMENT CANADA (CA) 1997-12-11 WO disclosed