2,5-Xylidine

2,5-Xylidine

SCHEMBL33981

Cc1ccc(C)c(N)c1.Cc1ccc(N)c(C)c1.Cc1ccc(N)cc1C.Cc1cccc(C)c1N.Cc1cccc(N)c1C

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.46
TDP1 Q9NUW8 4/20 0.46
CASP1 P29466 2/20 0.42
CD44 P16070 1/20 0.39
CYP3A4 P08684 6/20 0.36
ALOX15 P16050 2/20 0.36
TP53 P04637 1/20 0.36
THRB P10828 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TSHR P16473 4/20 0.34
PIK3CA P42336 1/20 0.34
LMNA P02545 2/20 0.33
HSD17B10 Q99714 2/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
PDE10A Q9Y233 1/20 0.33
NPC1 O15118 2/20 0.33
MITF O75030 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,5-Xylidine SCHEMBL28278837 0.89 ALDH1A1 (0.49) ALDH1A1TDP1CASP1CD44CYP3A4
2,5-Xylidine SCHEMBL28081135 0.88 ALDH1A1 (0.35) ALDH1A1TDP1CASP1CD44
2,5-Xylidine SCHEMBL9751765 0.82 ALDH1A1 (0.63) ALDH1A1TDP1CASP1CD44CYP3A4
SCHEMBL10830774 0.82 CYP3A4 (0.50) ALDH1A1TDP1CD44CYP3A4ALOX15
2,5-Xylidine SCHEMBL8448393 0.82 ALDH1A1 (0.68) ALDH1A1TDP1CASP1CD44CYP3A4
SCHEMBL9735305 0.81 ALDH1A1 (0.67) ALDH1A1TDP1CASP1CYP3A4ALOX15
SCHEMBL5083012 0.77 CD44 (0.56) ALDH1A1TDP1CD44CYP3A4ALOX15
2,5-Xylidine SCHEMBL11124717 0.77 TDP1 (0.77) ALDH1A1TDP1CASP1CD44CYP3A4
SCHEMBL15011 0.76 ALDH1A1 (0.44) ALDH1A1TDP1CASP1CD44CYP3A4
Orthotolidine SCHEMBL11207214 0.76 TDP1 (0.38) ALDH1A1TDP1CASP1CD44CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7008 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4615930-A1 HIGH-PERFORMANCE MORTAR COMPRISING TBX AND ANALOGUES fischerwerke GmbH & Co. KG (DE) 2025-09-17 EP claimed
EP-4085893-B1 TRANSPARENT, FRACTURE-RESISTANT POLYMERISATION RESINS FOR THE PRODUCTION OF DENTAL MOULDINGS IVOCLAR VIVADENT AG (LI) 2025-02-26 EP claimed
US-12162813-B2 Process for preparing 3,3,3-trifluoroprop-1-ene THE CHEMOURS COMPANY FC, LLC (US) 2024-12-10 US claimed
US-11998621-B2 Transparent, fracture-tough polymerization resins for the production of dental shaped bodies IVOCLAR VIVADENT AG (LI) 2024-06-04 US claimed
WO-2024099783-A1 HIGH-PERFORMANCE MORTAR COMPRISING TBX AND ANALOGUES FISCHERWERKE GMBH & CO. KG (DE) 2024-05-16 WO claimed
US-20230406790-A1 PROCESS FOR PREPARING 3,3,3-TRIFLUOROPROP-1-ENE THE CHEMOURS COMPANY FC, LLC. (US) 2023-12-21 US claimed
EP-4035552-B1 HYPOALLERGENIC FOOTWEAR AND METHOD FOR PREVENTING ALLERGIC CONTACT DERMATITIS ACD BINAR S R L (IT) 2023-11-01 EP claimed
US-20230265220-A1 Photopolymerizable Dental Composites With Rapid Curing And Low Shrinkage Stress IVOCLAR VIVADENT AG (LI) 2023-08-24 US claimed
US-11673980-B2 Photopolymerizable dental composites with rapid curing and low shrinkage stress IVOCLAR VIVADENT AG (LI) 2023-06-13 US claimed
US-20220370300-A1 Transparent, Fracture-Tough Polymerization Resins For The Production Of Dental Shaped Bodies IVOCLAR VIVADENT AG (LI) 2022-11-24 US claimed
US-4219626-A Accelerators for radical polymerization reactions with initiators free from peroxide groups BAYER AKTIENGESELLSCHAFT (DE) 1980-08-26 US claimed
US-4150054-A CONTACTING WITH ALCOHOL IN PRESENCE OF PHOSPHORIC ACID AND SALTS OF THE ALIPHATIC AMINO COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1979-04-17 US claimed
US-4129512-A POLYUREA THE BRITISH PETROLEUM COMPANY LIMITED (GB) 1978-12-12 US claimed
US-4125730-A Preparation of -aminoalkanoic acid arylamides BANYU PHARMACEUTICAL CO., LTD. (JP) 1978-11-14 US claimed
US-4107119-A MIXING AN AROMATIC PRIMARY AMINE WITH AN AQUEOUS SOLUTION OF AN ACCRYLAMIDE POLYMER OR COPOLYMER AND FORMALDEHYDE NIPPON KASEI CHEMICAL CO., LTD. (JP) 1978-08-15 US claimed
US-4062893-A SULFURIC ACID CATALYST NEW JAPAN CHEMICAL COMPANY, LIMITED (JA) 1977-12-13 US claimed
US-4026944-A TREATING DINITRONAPHTHALENE WITH HYDROGEN, HYDROGENATION CATALYST BAYER AKTIENGESELLSCHAFT (DT) 1977-05-31 US claimed
US-3980760-A Recovery of sulfur dioxide from gas mixtures ASARCO INCORPORATED (US) 1976-09-14 US claimed
US-3980759-A Recovery of sulfur dioxide from gas mixtures ASARCO INCORPORATED (US) 1976-09-14 US claimed
US-3959451-A Recovery of sulfur dioxide from gas mixtures ASARCO INCORPORATED (US) 1976-05-25 US claimed