Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
| ▸ | TK2 | O00142 | 7/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TK1 | P04183 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8447265 | 0.87 | KIF11 (0.50) | KIF11HDAC1HDAC2HDAC6HDAC3 | |
| SCHEMBL1884344 | 0.87 | KIF11 (0.50) | KIF11HDAC1HDAC2HDAC6HDAC3 | |
| SCHEMBL8870247 | 0.87 | KIF11 (0.50) | KIF11HDAC1HDAC2HDAC6HDAC3 | |
| SCHEMBL1880174 | 0.87 | KIF11 (0.50) | KIF11HDAC1HDAC2HDAC6HDAC3 | |
| SCHEMBL1884316 | 0.87 | KIF11 (0.50) | KIF11HDAC1HDAC2HDAC6HDAC3 | |
| SCHEMBL8448579 | 0.85 | KIF11 (0.49) | KIF11HDAC1HDAC2HDAC6HDAC3 | |
| SCHEMBL8869561 | 0.85 | KIF11 (0.52) | KIF11HDAC1HDAC2HDAC6HDAC3 | |
| Potassium Ion SCHEMBL9040682 | 0.85 | KIF11 (0.52) | KIF11HDAC1HDAC2HDAC6HDAC3 | |
| SCHEMBL18095446 | 0.83 | KIF11 (0.46) | KIF11HDAC1HDAC2HDAC6HDAC3 | |
| SCHEMBL1885700 | 0.81 | LTB4R (0.48) | KIF11HDAC6TK2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627942-B1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1999-09-15 | — | — | EP | disclosed |
| US-5919753-A | Cross-linking agent | NYCOMED IMAGING AS (NO) | 1999-07-06 | — | — | US | disclosed |
| US-5795562-A | BIODEGRADABLE POLYMER AS CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | NYCOMED IMAGING AS (NO) | 1998-08-18 | — | — | US | disclosed |
| US-5676925-A | USING POLYESTER OR ACRYLATE POLYMERS | NYCOMED IMAGING AS (NO) | 1997-10-14 | — | — | US | disclosed |
| US-5674468-A | A BIODEGRADABLE POLYESTER; USEFUL IN DIAGNOSTIC APPLICATIONS SUCH AS ULTRASOUND AND MAGNETIC RESONANCE IMAGING | NYCOMED IMAGING AS (NO) | 1997-10-07 | — | — | US | disclosed |
| EP-0577659-B1 | CROSS-LINKING AGENT | NYCOMED IMAGING AS (NO) | 1996-01-17 | — | — | EP | disclosed |
| EP-0627942-A1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1994-12-14 | — | — | EP | disclosed |
| EP-0577659-A1 | CROSS-LINKING AGENT. | HOLMES MICHAEL JOHN (GB) | 1994-01-12 | — | — | EP | disclosed |
| WO-1993017718-A1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING A/S (NO) | 1993-09-16 | — | — | WO | disclosed |
| WO-1992017436-A1 | CROSS-LINKING AGENT | HOLMES, MICHAEL, JOHN (GB) | 1992-10-15 | — | — | WO | disclosed |