Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8452030 | 1.00 | CNR1 (0.42) | CNR1CNR2NFE2L2CYP1A1CYP1A2 | |
| SCHEMBL9276716 | 0.90 | MIF (0.49) | CNR1CNR2NFE2L2PTGS1PTGS2 | |
| SCHEMBL7238597 | 0.85 | TLR8 (0.38) | CNR1CNR2NPC1TP53PKM | |
| SCHEMBL7238598 | 0.85 | TLR8 (0.38) | CNR1CNR2NPC1TP53PKM | |
| SCHEMBL23298960 | 0.85 | CNR1 (0.40) | CNR1CNR2NPC1TP53PKM | |
| SCHEMBL7735973 | 0.85 | CNR1 (0.40) | CNR1CNR2NPC1TP53PKM | |
| SCHEMBL7237152 | 0.82 | PDE5A (0.40) | CNR1CNR2 | |
| SCHEMBL7237157 | 0.82 | PDE5A (0.40) | CNR1CNR2 | |
| SCHEMBL12976427 | 0.81 | HTR2A (0.36) | THRBPDK2 | |
| SCHEMBL12739593 | 0.79 | NFE2L2 (0.40) | CNR1CNR2NFE2L2CYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914071-A | Difluoroethylene compounds and liquid crystal compositions containing them | ASAHI GLASS COMPANY LTD. (JP) | 1999-06-22 | — | — | US | disclosed |
| US-5663463-A | Difluoroethylene compounds and liquid crystal compositions containing them | ASAHI GLASS COMPANY LTD. (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0560382-B1 | Difluoroethylene compounds and liquid crystal compositions containing them | ASAHI GLASS CO LTD (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5516949-A | LOW VISCOSITY AND PHOTOSTABLE | ASAHI GLASS COMPANY LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5419851-A | Difluoro-derivative compounds and liquid crystal compositions containing them | ASAHI GLASS COMPANY LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0628528-A1 | DIFLUORIDE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | ASAHI GLASS COMPANY LTD. (JP) | 1994-12-14 | — | — | EP | disclosed |
| EP-0560382-A1 | Difluoroethylene compounds and liquid crystal compositions containing them | ASAHI GLASS COMPANY LTD. (JP) | 1993-09-15 | — | — | EP | disclosed |