SCHEMBL7735973

SCHEMBL7735973

CCCc1ccc(C=O)c(F)c1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
CDK1 P06493 1/20 0.40
LPL P06858 1/20 0.37
LIPG Q9Y5X9 1/20 0.37
THRB P10828 2/20 0.36
ALDH1A1 P00352 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CA2 P00918 1/20 0.35
GPR84 Q9NQS5 1/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
TP53 P04637 1/20 0.35
PKM P14618 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSD17B10 Q99714 1/20 0.35
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1219815 0.89 CDK1 (0.45) CDK1THRBALDH1A1CA2NPC1
SCHEMBL502476 0.86 RARB (0.47) LPLLIPGTHRBNPC1RAB9A
SCHEMBL8448672 0.85 CNR1 (0.42) CNR1CNR2LPLLIPGTHRB
SCHEMBL30191458 0.85 LMNA (0.38) CDK1ALDH1A1L3MBTL1NPC1RAB9A
SCHEMBL12109807 0.85 LMNA (0.38) CDK1ALDH1A1L3MBTL1NPC1RAB9A
SCHEMBL8452030 0.85 CNR1 (0.42) CNR1CNR2LPLLIPGTHRB
SCHEMBL27679855 0.82 CDK1 (0.47) CNR1CNR2CDK1LPLLIPG
SCHEMBL23298960 0.81 CNR1 (0.40) CNR1CNR2LPLLIPGTHRB
SCHEMBL21901990 0.81 CDK1 (0.43) CDK1ALDH1A1CA2GAA
SCHEMBL12976274 0.80 RARB (0.42) NPC1RAB9ATP53PKMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6468606-B1 LOW VISCOSITY, HIGH DIELECTRIC ANISOTROPY, LOW OPTICAL ANISOTROPY, EXCELLENT LOW TEMPERATURE COMPATIBILITY WITH OTHER LIQUID CRYSTALLINE COMPOUNDS; 3,4,5-TRIFLUOROPHENYL-(2-FLUORO-4-(TRANS-4-PROPYLCYCLOHEXYL))BENZOATE CHISSO CORPORATION (JP) 2002-10-22 US disclosed
EP-0808825-B1 PHENYL BENZOATE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS CHISSO CORP (JP) 2001-09-12 EP disclosed
US-5922243-A LOW VISCOSITY, HIGH DIELECTRIC AND LOW OPTICAL ANISOTROPY, EXCELLENT COMPATIBILITY CHISSO CORPORATION (JP) 1999-07-13 US disclosed
EP-0808825-A1 PHENYL BENZOATE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS CHISSO CORPORATION (JP) 1997-11-26 EP disclosed