Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9269862 | 0.79 | TDP1 (0.55) | ALDH1A1TDP1KMT2AMAPK1HIF1A | |
| SCHEMBL28660559 | 0.78 | MAPK1 (0.49) | ALDH1A1TDP1KMT2AMAPK1HIF1A | |
| SCHEMBL27773060 | 0.76 | TDP1 (0.52) | ALDH1A1TDP1KMT2AMAPK1HIF1A | |
| SCHEMBL16290120 | 0.75 | TDP1 (0.50) | ALDH1A1TDP1KMT2AMAPK1HIF1A | |
| SCHEMBL12425826 | 0.75 | TDP1 (0.50) | ALDH1A1TDP1KMT2AMAPK1HIF1A | |
| SCHEMBL1713120 | 0.75 | TDP1 (0.50) | ALDH1A1TDP1KMT2AMAPK1HIF1A | |
| SCHEMBL38654273 | 0.75 | TDP1 (0.50) | ALDH1A1TDP1KMT2AMAPK1HIF1A | |
| SCHEMBL8496636 | 0.75 | TDP1 (0.50) | ALDH1A1TDP1KMT2AMAPK1HIF1A | |
| SCHEMBL13479250 | 0.74 | TDP1 (0.49) | ALDH1A1TDP1KMT2AMAPK1HIF1A | |
| SCHEMBL20288884 | 0.74 | LMNA (0.54) | ALDH1A1TDP1KMT2AMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502690-B1 | Cyclopropane derivative | AJINOMOTO KK (JP) | 1999-12-01 | — | — | EP | disclosed |
| US-5449840-A | Viricides | AJINOMOTO CO., INC. (JP) | 1995-09-12 | — | — | US | disclosed |
| US-5342840-A | Viricides | AJINOMOTO CO., INC. (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0502690-A2 | Cyclopropane derivative | Ajinomoto Co., Inc. (JP) | 1992-09-09 | — | — | EP | disclosed |