Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CPT2 | P23786 | 6/20 | 0.50 |
| ▸ | CPT1A | P50416 | 6/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844903 | 0.88 | EP300 (0.51) | PABPC1ALDH1A1MAPK1HTTLMNA | |
| SCHEMBL845206 | 0.84 | CYP2C9 (0.52) | PABPC1ALDH1A1MAPK1HTTLMNA | |
| SCHEMBL845226 | 0.84 | ALDH1A1 (0.56) | PABPC1ALDH1A1MAPK1HTTLMNA | |
| SCHEMBL13272444 | 0.84 | ALDH1A1 (0.56) | PABPC1ALDH1A1MAPK1HTTLMNA | |
| SCHEMBL1030175 | 0.84 | ALDH1A1 (0.56) | PABPC1ALDH1A1MAPK1HTTLMNA | |
| SCHEMBL845111 | 0.84 | ALDH1A1 (0.56) | PABPC1ALDH1A1MAPK1HTTLMNA | |
| SCHEMBL845205 | 0.84 | ALDH1A1 (0.56) | PABPC1ALDH1A1MAPK1HTTLMNA | |
| SCHEMBL15116912 | 0.84 | ALDH1A1 (0.56) | PABPC1ALDH1A1MAPK1HTTLMNA | |
| SCHEMBL873777 | 0.84 | EP300 (0.49) | PABPC1ALDH1A1LMNACYP2C19CPT2 | |
| SCHEMBL845567 | 0.83 | ALDH1A1 (0.50) | PABPC1ALDH1A1MAPK1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |