Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 2/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CPT2 | P23786 | 1/20 | 0.46 |
| ▸ | CPT1A | P50416 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844903 | 0.95 | EP300 (0.51) | EP300CREBBPALDH1A1CPT2CPT1A | |
| SCHEMBL10120083 | 0.87 | CPT2 (0.46) | EP300CREBBPALDH1A1CPT2CPT1A | |
| SCHEMBL844882 | 0.84 | PABPC1 (0.59) | EP300CREBBPALDH1A1GAACPT2 | |
| SCHEMBL845373 | 0.80 | ALDH1A1 (0.57) | ALDH1A1GAATSHRNPSR1POLB | |
| SCHEMBL845382 | 0.80 | EP300 (0.52) | EP300CREBBPALDH1A1GAATSHR | |
| SCHEMBL845342 | 0.78 | ALDH1A1 (0.59) | ALDH1A1GAATSHRNPSR1POLB | |
| SCHEMBL845206 | 0.77 | CYP2C9 (0.52) | EP300CREBBPALDH1A1GAATSHR | |
| SCHEMBL844898 | 0.75 | ALDH1A1 (0.54) | EP300CREBBPALDH1A1TSHRNPSR1 | |
| SCHEMBL10119342 | 0.75 | ALDH1A1 (0.45) | EP300CREBBPALDH1A1GAATSHR | |
| SCHEMBL845251 | 0.74 | PABPC1 (0.50) | EP300CREBBPALDH1A1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |