Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.47 |
| ▸ | RELA | Q04206 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 3/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9477526 | 0.92 | NPC1 (0.57) | NPC1LMNASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL9457633 | 0.92 | NPC1 (0.57) | NPC1LMNASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL9406028 | 0.92 | NPC1 (0.57) | NPC1LMNASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL9406307 | 0.92 | NPC1 (0.57) | NPC1LMNASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL9406219 | 0.92 | NPC1 (0.57) | NPC1LMNASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL8729949 | 0.91 | THRA (0.44) | NPC1LMNASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL8449005 | 0.90 | LMNA (0.49) | NPC1LMNASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL9405742 | 0.88 | RARB (0.53) | NPC1LMNASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL9405901 | 0.88 | RARB (0.53) | NPC1LMNASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL9406583 | 0.88 | RARB (0.53) | NPC1LMNASMN1; SMN2NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861109-A | Liquid crystal materials, mixtures and devices | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND OF DEFENCE EVALUATION RESEARCH AGENCY (GB) | 1999-01-19 | — | — | US | disclosed |
| EP-0703955-B1 | LIQUID CRYSTAL MATERIALS, MIXTURES AND DEVICES | SECR DEFENCE BRIT (GB) | 1998-11-11 | — | — | EP | disclosed |
| EP-0703955-A1 | LIQUID CRYSTAL MATERIALS, MIXTURES AND DEVICES | SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOV. OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1996-04-03 | — | — | EP | disclosed |
| WO-1994029405-A1 | LIQUID CRYSTAL MATERIALS, MIXTURES AND DEVICES | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1994-12-22 | — | — | WO | disclosed |