Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8449088 | 1.00 | P2RX7 (0.33) | P2RX7HCRTR1HCRTR2KCNH2EPHX2 | |
| SCHEMBL8449096 | 1.00 | P2RX7 (0.33) | P2RX7HCRTR1HCRTR2KCNH2EPHX2 | |
| SCHEMBL8452589 | 0.97 | P2RX7 (0.35) | P2RX7HCRTR1HCRTR2KCNH2EPHX2 | |
| SCHEMBL8452592 | 0.97 | P2RX7 (0.35) | P2RX7HCRTR1HCRTR2KCNH2EPHX2 | |
| SCHEMBL8452587 | 0.97 | P2RX7 (0.35) | P2RX7HCRTR1HCRTR2KCNH2EPHX2 | |
| SCHEMBL8452265 | 0.89 | NAAA (0.35) | P2RX7HCRTR1HCRTR2EPHX2CHRM4 | |
| SCHEMBL8452271 | 0.89 | NAAA (0.35) | P2RX7HCRTR1HCRTR2EPHX2CHRM4 | |
| SCHEMBL8452273 | 0.89 | NAAA (0.35) | P2RX7HCRTR1HCRTR2EPHX2CHRM4 | |
| SCHEMBL8452267 | 0.89 | NAAA (0.35) | P2RX7HCRTR1HCRTR2EPHX2CHRM4 | |
| SCHEMBL8449352 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679707-B1 | Liquid crystalline compound, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5720899-A | Liquid crystalline compound, liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 1998-02-24 | — | — | US | disclosed |
| US-5653911-A | Liquid crystalline compound liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 1997-08-05 | — | — | US | disclosed |
| EP-0679707-A1 | Liquid crystalline compound, liquid crystal composition and liquid crystal display element | Chisso Corporation (JP) | 1995-11-02 | — | — | EP | disclosed |