Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463367 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNAGPR119DPP8 | |
| SCHEMBL8448791 | 0.85 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAGPR119DPP8 | |
| SCHEMBL8449087 | 0.85 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAGPR119DPP8 | |
| SCHEMBL1993903 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNAGPR119NR1D1 | |
| SCHEMBL1993906 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNAGPR119NR1D1 | |
| SCHEMBL7455301 | 0.79 | DPP8 (0.40) | ALDH1A1MAPTLMNADPP8DPP9 | |
| SCHEMBL8444893 | 0.79 | DPP8 (0.40) | ALDH1A1MAPTLMNADPP8DPP9 | |
| SCHEMBL5724167 | 0.79 | ALDH1A1 (0.67) | ALDH1A1MAPTLMNAGPR119HPGD | |
| SCHEMBL7463372 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAGPR119DPP8 | |
| SCHEMBL8449180 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAGPR119DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900797-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1999-03-10 | — | — | EP | disclosed |