Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8449186 | 1.00 | ESR2 (0.37) | ESR2HTR3ADRD2IDO1SLC18A3 | |
| SCHEMBL8449197 | 1.00 | ESR2 (0.37) | ESR2HTR3ADRD2IDO1SLC18A3 | |
| SCHEMBL8453682 | 0.89 | HTR3A (0.37) | HTR3ADRD2SLC18A3CYP2C9LSS | |
| SCHEMBL8453696 | 0.89 | HTR3A (0.37) | HTR3ADRD2SLC18A3CYP2C9LSS | |
| SCHEMBL8453693 | 0.89 | HTR3A (0.37) | HTR3ADRD2SLC18A3CYP2C9LSS | |
| SCHEMBL8453684 | 0.89 | HTR3A (0.37) | HTR3ADRD2SLC18A3CYP2C9LSS | |
| SCHEMBL8452414 | 0.88 | ESR2 (0.38) | ESR2CYP2C9ESR1CYP3A4HDAC2 | |
| SCHEMBL8452418 | 0.88 | ESR2 (0.38) | ESR2CYP2C9ESR1CYP3A4HDAC2 | |
| SCHEMBL8452423 | 0.88 | ESR2 (0.38) | ESR2CYP2C9ESR1CYP3A4HDAC2 | |
| SCHEMBL8518725 | 0.86 | DRD2 (0.44) | ESR2HTR3ADRD2IDO1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679707-B1 | Liquid crystalline compound, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5720899-A | Liquid crystalline compound, liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 1998-02-24 | — | — | US | disclosed |
| US-5653911-A | Liquid crystalline compound liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 1997-08-05 | — | — | US | disclosed |
| EP-0679707-A1 | Liquid crystalline compound, liquid crystal composition and liquid crystal display element | Chisso Corporation (JP) | 1995-11-02 | — | — | EP | disclosed |