Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1780483 | 0.89 | ALDH1A1 (0.40) | LMNAHPGDSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL23582550 | 0.89 | ALDH1A1 (0.40) | LMNAHPGDSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL3503877 | 0.88 | LMNA (0.46) | LMNAHPGDSMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL344570 | 0.81 | LMNA (0.41) | LMNAHPGDSMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL22468381 | 0.81 | LMNA (0.36) | LMNAHPGDSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL16886295 | 0.80 | EPHX2 (0.44) | LMNAHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL7440334 | 0.78 | LMNA (0.34) | LMNAHPGDALDH1A1GAATSHR | |
| SCHEMBL12539837 | 0.78 | LMNA (0.39) | LMNAHPGDSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL25317162 | 0.78 | LMNA (0.39) | LMNAHPGDSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL25313461 | 0.78 | LMNA (0.39) | LMNAHPGDSMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234867-A1 | SULFONAMIDE HAVING MMP 7-INHIBITING ACTION | 大正製薬株式会社 | 2022-11-10 | — | — | WO | disclosed |
| EP-2432555-A1 | N-(HETERO)ARYL-PYRROLIDINE DERIVATIVES OF PYRAZOL-4-YL-PYRROLO[2,3-d]PYRIMIDINES AND PYRROL-3-YL-PYRROLO[2,3-d]PYRIMIDINES AS JANUS KINASE INHIBITORS | Incyte Corporation (US) | 2012-03-28 | — | — | EP | disclosed |