Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.50 |
| ▸ | TACR1 | P25103 | 2/20 | 0.50 |
| ▸ | MME | P08473 | 7/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 2/20 | 0.40 |
| ▸ | MC5R | P33032 | 2/20 | 0.40 |
| ▸ | MC3R | P41968 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573808 | 0.95 | ACE (0.56) | ACETACR1MMECTSLCTSB | |
| SCHEMBL7573818 | 0.95 | ACE (0.56) | ACETACR1MMECTSLCTSB | |
| SCHEMBL8451268 | 0.89 | MME (0.46) | ACETACR1MMECTSLPTGES | |
| SCHEMBL8450193 | 0.89 | TACR1 (0.52) | ACETACR1MMECTSLCTSB | |
| SCHEMBL27464504 | 0.88 | ACE (0.60) | ACETACR1MMECTSLCTSB | |
| SCHEMBL8446481 | 0.86 | MME (0.62) | ACETACR1MMECTSLCTSB | |
| SCHEMBL7569373 | 0.85 | ACE (0.64) | ACEMMEPTPN2PTPN1CDC25B | |
| SCHEMBL7569381 | 0.85 | ACE (0.64) | ACEMMEPTPN2PTPN1CDC25B | |
| SCHEMBL8447138 | 0.85 | MME (0.58) | ACETACR1MMECTSLCTSB | |
| SCHEMBL7567864 | 0.85 | ACE (0.51) | ACEMMEPTPN1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |