Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 3/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
| ▸ | EP300 | Q09472 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448390 | 1.00 | PDE3A (0.47) | PDE3AALDH1A1KDM4EHPGDADRA1A | |
| SCHEMBL8448373 | 1.00 | PDE3A (0.47) | PDE3AALDH1A1KDM4EHPGDADRA1A | |
| SCHEMBL8449919 | 0.93 | ALDH1A1 (0.42) | PDE3AALDH1A1KDM4EHPGDADRA1A | |
| SCHEMBL8445987 | 0.93 | ALDH1A1 (0.42) | PDE3AALDH1A1KDM4EHPGDADRA1A | |
| SCHEMBL8445978 | 0.93 | ALDH1A1 (0.42) | PDE3AALDH1A1KDM4EHPGDADRA1A | |
| SCHEMBL8578278 | 0.93 | ALDH1A1 (0.42) | PDE3AALDH1A1KDM4EHPGDADRA1A | |
| SCHEMBL9583275 | 0.93 | ALDH1A1 (0.49) | PDE3AALDH1A1KDM4EHPGDADRA1A | |
| SCHEMBL9582923 | 0.89 | ALDH1A1 (0.47) | PDE3AALDH1A1KDM4EHPGDADRA1A | |
| SCHEMBL8448237 | 0.86 | ALDH1A1 (0.62) | PDE3AALDH1A1KDM4EHPGDADRA1A | |
| SCHEMBL8447891 | 0.86 | ALDH1A1 (0.62) | PDE3AALDH1A1KDM4EHPGDADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942916-A2 | NUCLEOSIDES | Medivir Aktiebolag (SE) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998021223-A1 | NUCLEOSIDES | MEDIVIR AB (SE) | 1998-05-22 | — | — | WO | disclosed |