Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 3/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 2/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9582923 | 0.95 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL8448390 | 0.93 | PDE3A (0.47) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL8449563 | 0.93 | PDE3A (0.47) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL8448373 | 0.93 | PDE3A (0.47) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL8449919 | 0.91 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL8578278 | 0.91 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL8445978 | 0.91 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL8445987 | 0.91 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL9583455 | 0.87 | ALDH1A1 (0.40) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL9583536 | 0.84 | CDK1 (0.46) | ALDH1A1LMNAPRKCAPRKCEPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250535-A | Herpes virus; nontoxic; side effect reduction; humans and veterinary medicine | SYNTEX INC. (US) | 1993-10-05 | — | — | US | disclosed |
| US-4803271-A | Process for preparing guanine derivatives | SYNTEX (U.S.A.) INC. (US) | 1989-02-07 | — | — | US | disclosed |
| US-4612314-A | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1986-09-16 | — | — | US | disclosed |
| EP-0085424-A2 | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl)purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1983-08-10 | — | — | EP | disclosed |