Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8449881 | 1.00 | NAAA (0.34) | NAAAKMT2AMEN1CYP2C9POLB | |
| SCHEMBL13367433 | 0.92 | NAAA (0.43) | NAAAKMT2AMEN1CYP2C9POLB | |
| SCHEMBL7900518 | 0.89 | NAAA (0.40) | NAAAKMT2AMEN1CYP2C9POLB | |
| SCHEMBL10416941 | 0.89 | NAAA (0.40) | NAAAKMT2AMEN1CYP2C9POLB | |
| SCHEMBL7908266 | 0.89 | NAAA (0.40) | NAAAKMT2AMEN1CYP2C9POLB | |
| SCHEMBL7900514 | 0.89 | NAAA (0.40) | NAAAKMT2AMEN1CYP2C9POLB | |
| SCHEMBL11218030 | 0.89 | NAAA (0.40) | NAAAKMT2AMEN1CYP2C9POLB | |
| SCHEMBL10759371 | 0.89 | NAAA (0.40) | NAAAKMT2AMEN1CYP2C9POLB | |
| SCHEMBL8455344 | 0.88 | CYP19A1 (0.40) | KMT2AMEN1HPGDGAACYP19A1 | |
| SCHEMBL8455346 | 0.88 | CYP19A1 (0.40) | KMT2AMEN1HPGDGAACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5976408-A | Acrylonitrile derivative, liquid crystal composition, and liquid crystal display device | CHISSO CORPORATION (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0820983-A1 | ACRYLONITRILE DERIVATIVES, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 1998-01-28 | — | — | EP | disclosed |