SCHEMBL8455346

SCHEMBL8455346

CCC1CCC(C(=O)OC2CCC(C=O)CC2)CC1

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.40
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8455344 1.00 CYP19A1 (0.40) CYP19A1MEN1KMT2AGAAHPGD
SCHEMBL8449881 0.88 NAAA (0.34) CYP19A1MEN1KMT2AGAAHPGD
SCHEMBL8449879 0.88 NAAA (0.34) CYP19A1MEN1KMT2AGAAHPGD
SCHEMBL13878839 0.87
SCHEMBL13878838 0.87
SCHEMBL13367433 0.85 NAAA (0.43) MEN1KMT2AGAAHPGD
SCHEMBL8456941 0.85 CYP19A1 (0.36) CYP19A1MEN1KMT2A
SCHEMBL8456949 0.85 CYP19A1 (0.36) CYP19A1MEN1KMT2A
SCHEMBL8456945 0.85 CYP19A1 (0.36) CYP19A1MEN1KMT2A
SCHEMBL23130440 0.85 TP53 (0.38) GAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5976408-A Acrylonitrile derivative, liquid crystal composition, and liquid crystal display device CHISSO CORPORATION (JP) 1999-11-02 US disclosed
EP-0820983-A1 ACRYLONITRILE DERIVATIVES, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY DEVICE CHISSO CORPORATION (JP) 1998-01-28 EP disclosed