Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8449968 | 1.00 | CACNA1G (0.39) | CACNA1GCACNA1HCACNA1IDRD2DRD3 | |
| SCHEMBL7769896 | 0.91 | CACNA1G (0.37) | CACNA1GCACNA1HCACNA1IDRD2DRD3 | |
| SCHEMBL7769893 | 0.91 | CACNA1G (0.37) | CACNA1GCACNA1HCACNA1IDRD2DRD3 | |
| SCHEMBL7769899 | 0.91 | CACNA1G (0.37) | CACNA1GCACNA1HCACNA1IDRD2DRD3 | |
| SCHEMBL8449440 | 0.85 | HTT (0.34) | CACNA1GCACNA1HCACNA1ILMNARAB9A | |
| SCHEMBL8449431 | 0.85 | HTT (0.34) | CACNA1GCACNA1HCACNA1ILMNARAB9A | |
| SCHEMBL8372074 | 0.84 | KDM1A (0.40) | DRD2LIPESPHK1 | |
| SCHEMBL8372072 | 0.84 | KDM1A (0.40) | DRD2LIPESPHK1 | |
| SCHEMBL8453635 | 0.82 | FFAR4 (0.35) | DRD2DRD3SPHK1HRH3 | |
| SCHEMBL8453632 | 0.82 | FFAR4 (0.35) | DRD2DRD3SPHK1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004478-A | LIQUID CRYSTAL | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-12-21 | — | — | US | disclosed |
| EP-0732335-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-09-18 | — | — | EP | disclosed |