Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 3/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450051 | 1.00 | KDM4E (0.38) | KDM4EMEN1KMT2AMAPTCYP2C9 | |
| SCHEMBL8457022 | 0.92 | KDM4E (0.40) | KDM4EMEN1KMT2AMAPTCYP2C9 | |
| SCHEMBL8457024 | 0.92 | KDM4E (0.40) | KDM4EMEN1KMT2AMAPTCYP2C9 | |
| SCHEMBL8457107 | 0.88 | SCN1A (0.36) | MEN1KMT2AMAPTSMN1; SMN2SCN1A | |
| SCHEMBL8457108 | 0.88 | SCN1A (0.36) | MEN1KMT2AMAPTSMN1; SMN2SCN1A | |
| SCHEMBL8457119 | 0.88 | SCN1A (0.36) | MEN1KMT2AMAPTSMN1; SMN2SCN1A | |
| SCHEMBL8457114 | 0.88 | SCN1A (0.36) | MEN1KMT2AMAPTSMN1; SMN2SCN1A | |
| SCHEMBL8453740 | 0.88 | HSD11B1 (0.39) | MAPTSMN1; SMN2HSD11B1EPHX2NPC1 | |
| SCHEMBL8453744 | 0.88 | HSD11B1 (0.39) | MAPTSMN1; SMN2HSD11B1EPHX2NPC1 | |
| SCHEMBL8453748 | 0.88 | HSD11B1 (0.39) | MAPTSMN1; SMN2HSD11B1EPHX2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5976408-A | Acrylonitrile derivative, liquid crystal composition, and liquid crystal display device | CHISSO CORPORATION (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0820983-A1 | ACRYLONITRILE DERIVATIVES, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 1998-01-28 | — | — | EP | disclosed |