Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.38 |
| ▸ | FAAH | O00519 | 5/20 | 0.38 |
| ▸ | STS | P08842 | 4/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8453748 | 1.00 | HSD11B1 (0.39) | HSD11B1PREPEPHX2FAAHSTS | |
| SCHEMBL8453736 | 1.00 | HSD11B1 (0.39) | HSD11B1PREPEPHX2FAAHSTS | |
| SCHEMBL8453740 | 1.00 | HSD11B1 (0.39) | HSD11B1PREPEPHX2FAAHSTS | |
| SCHEMBL8454908 | 0.92 | HSD11B1 (0.41) | HSD11B1PREPEPHX2FAAHSTS | |
| SCHEMBL8454904 | 0.92 | HSD11B1 (0.41) | HSD11B1PREPEPHX2FAAHSTS | |
| SCHEMBL8454915 | 0.92 | HSD11B1 (0.41) | HSD11B1PREPEPHX2FAAHSTS | |
| SCHEMBL8454902 | 0.92 | HSD11B1 (0.41) | HSD11B1PREPEPHX2FAAHSTS | |
| SCHEMBL8450055 | 0.88 | KDM4E (0.38) | HSD11B1EPHX2NPC1HTTRAB9A | |
| SCHEMBL8450051 | 0.88 | KDM4E (0.38) | HSD11B1EPHX2NPC1HTTRAB9A | |
| SCHEMBL8457119 | 0.87 | SCN1A (0.36) | EPHX2STSNPC1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5976408-A | Acrylonitrile derivative, liquid crystal composition, and liquid crystal display device | CHISSO CORPORATION (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0820983-A1 | ACRYLONITRILE DERIVATIVES, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 1998-01-28 | — | — | EP | disclosed |